Evidence map›Paper›PMID 41002350›Full record

ReviewBiosensors2025

Recent Advances in Flexible Materials for Wearable Optical Biosensors.

Linyan Xie, Kai Yang, Mengfei Wang, Wenli Hou, Qiongqiong Ren

Abstract readReview
In one paragraph

Review in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linyan XieSchool of Mathematical Medicine and School of Medical Engineering, Henan Medical University, Xinxiang 453003, China.
Kai YangSchool of Mathematical Medicine and School of Medical Engineering, Henan Medical University, Xinxiang 453003, China.
Mengfei WangSchool of Mathematical Medicine and School of Medical Engineering, Henan Medical University, Xinxiang 453003, China.
Wenli HouSchool of Mathematical Medicine and School of Medical Engineering, Henan Medical University, Xinxiang 453003, China.
Qiongqiong RenSchool of Mathematical Medicine and School of Medical Engineering, Henan Medical University, Xinxiang 453003, China.ORCID 0000-0002-8023-9753

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of flexible materials with optical sensing technologies has advanced wearable optical biosensors, offering significant potential in personalized medicine, health monitoring, and disease prevention. This review summarizes the recent advancements in flexible materials for wearable optical biosensors, with a focus on materials such as polymer substrates, nanostructured materials, MXenes, hydrogels, and textile-based integrated platforms. These materials enhance the functionality, sensitivity, and adaptability of sensors, particularly in wearable applications. The review also explores various optical sensing mechanisms, including surface plasmon resonance (SPR), optical fiber sensing, fluorescence sensing, chemiluminescence, and surface-enhanced Raman spectroscopy (SERS), emphasizing their role in improving the detection capabilities for biomarkers, physiological parameters, and environmental pollutants. Despite significant advancements, critical challenges remain in the fabrication and practical deployment of flexible optical biosensors, particularly regarding the long-term stability of materials under dynamic environments, maintaining reliable biocompatibility during prolonged skin contact, and minimizing signal interference caused by motion artifacts and environmental fluctuations. Addressing these issues is vital to ensure robustness and accuracy in real-world applications. Looking forward, future research should emphasize the development of multifunctional and miniaturized devices, the integration of wireless communication and intelligent data analytics, and the improvement of environmental resilience. Such innovations are expected to accelerate the transition of flexible optical biosensors from laboratory research to practical clinical and consumer healthcare applications, paving the way for intelligent health management and early disease diagnostics. Overall, flexible optical biosensors hold great promise in personalized health management, early disease diagnosis, and continuous physiological monitoring, with the potential to revolutionize the healthcare sector.

Indexed as

Biosensing TechniquesWearable Electronic DevicesHumansNanostructuresSpectrum Analysis, RamanSurface Plasmon Resonancedisease preventionflexible materialshealth monitoringoptical sensingwearable biosensors

Identifiers

PMID41002350
PMCPMC12467128

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.