Evidence map›Paper›PMID 41003103›Full record

ArticleJournal of personalized medicine2025

Enhancing LI-RADS Through Semi-Automated Quantification of HCC Lesions.

Anna Jöbstl, Piera Maria Tierno, Anna-Katharina Gerstner, Gudrun Maria Feuchtner, Benedikt Schaefer, Herbert Tilg, Gerlig Widmann

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Article in Journal of personalized medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anna JöbstlDepartment of Radiology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Tyrol, Austria.ORCID 0009-0007-5124-4856
Piera Maria TiernoDepartment of Radiology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Tyrol, Austria.
Anna-Katharina GerstnerDepartment of Radiology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Tyrol, Austria.ORCID 0000-0002-4451-5036
Gudrun Maria FeuchtnerDepartment of Radiology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Tyrol, Austria.ORCID 0000-0001-6755-4399
Benedikt SchaeferDepartment of Internal Medicine I, Gastroenterology, Hepatology and Endocrinology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Tyrol, Austria.ORCID 0000-0001-8690-2774
Herbert TilgDepartment of Internal Medicine I, Gastroenterology, Hepatology and Endocrinology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Tyrol, Austria.ORCID 0000-0002-4235-2579
Gerlig WidmannDepartment of Radiology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Tyrol, Austria.ORCID 0000-0002-7255-0672

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesHepatocellular carcinoma (HCC) is the most common primary malignant tumour of the liver. In a cirrhotic liver, each nodule larger than 10 mm demands further work-up using CT or MRI. The Liver Imaging Reporting and Data System (LI-RADS) is still based on visual assessment and measurements. The purpose of this study was to evaluate whether semi-automated quantification of visual LR-5 lesions is appropriate and can objectify HCC classification for personalized radiomic research.

methodsA total of 52 HCC patients (median age 67 years, 17% females, 83% males) from a retrospective data collection were evaluated visually and compared by the results using an oncology software with features of LI-RADS-based structured tumour evaluation and documentation, semi-automated tumour segmentation, and texture analysis.

resultsSoftware-based evaluation of non-rim arterial-phase hyperenhancement (APHE) and non-peripheral washout, as well as the LI-RADS-score, showed no statistically significant differences compared with visual assessment (

conclusionsThe presented work may serve as an outlook for LI-RADS-based automated qualitative and quantitative evaluation. Future research may show if texture analysis can be used to foster personalized medical approaches in HCC.

Indexed as

computed tomographyhepatocellular carcinomaLI-RADSsegmentationtexture analysis

Identifiers

PMID41003103
PMCPMC12470679

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.