Evidence map›Paper›PMID 41003176›Full record

ArticleJournal of fungi (Basel, Switzerland)2025

Shifting Paradigms in Antifungal Prophylaxis and Their Effects on Candidemia Outcomes in Hematological Malignancies: A 14-Year Experience from a Single Tertiary Center.

Fazıl Çağrı Hunutlu, Fahir Özkalemkaş, Beyza Ener, Dilay Demirayak, Büşra Çalışır, Hikmet Öztop, İbrahim Ethem Pınar, Vildan Gürsoy, Tuba Ersal, Tuba Güllü Koca and 2 more

Abstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fazıl Çağrı HunutluDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Bursa Uludag University, Gorukle Campus, Bursa 16059, Turkey.ORCID 0000-0002-4991-9830
Fahir ÖzkalemkaşDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Bursa Uludag University, Gorukle Campus, Bursa 16059, Turkey.ORCID 0000-0001-9710-134X
Beyza EnerDepartment of Microbiology, Faculty of Medicine, Bursa Uludag University, Bursa 16059, Turkey.
Dilay DemirayakDepartment of Gastroenterology, Bilecik Education and Research Hospital, Bilecik 11000, Turkey.ORCID 0000-0001-5926-6813
Büşra ÇalışırDepartment of Microbiology, Faculty of Medicine, Bursa Uludag University, Bursa 16059, Turkey.ORCID 0000-0001-6257-5422
Hikmet ÖztopDepartment of Internal Medicine, Faculty of Medicine, Bursa Uludag University, Bursa 16059, Turkey.ORCID 0000-0002-0199-3791
İbrahim Ethem PınarDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Bursa Uludag University, Gorukle Campus, Bursa 16059, Turkey.ORCID 0000-0001-9907-1498
Vildan GürsoyDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Bursa Uludag University, Gorukle Campus, Bursa 16059, Turkey.
Tuba ErsalDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Bursa Uludag University, Gorukle Campus, Bursa 16059, Turkey.ORCID 0000-0001-5419-3221
Tuba Güllü KocaDepartment of Hematology, Bursa City Hospital, Bursa 16059, Turkey.
Emin Halis AkalınDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Bursa Uludag University, Bursa 16059, Turkey.ORCID 0000-0001-7530-1279
Vildan ÖzkocamanDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Bursa Uludag University, Gorukle Campus, Bursa 16059, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evolving antifungal prophylaxis approaches have reshaped candidemia patterns and outcomes in hematological malignancy (HM) patients. This study aimed to evaluate temporal changes in candidemia incidence, species distribution, and factors associated with mortality in relation to prophylaxis practices. Adult HM patients with candidemia between 2009 and 2023 were included. Clinical and microbiological data were analyzed, and candidemia rates were compared across different prophylaxis periods. Sixty-six patients were identified, with acute myeloid leukemia (AML) being the most common underlying malignancy (40.9%). Non-albicans

Indexed as

acute myeloid leukemiaantifungal prophylaxisCandida tropicaliscandidemiahematological malignanciesposaconazole

Identifiers

PMID41003176
PMCPMC12471038

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.