Evidence map›Paper›PMID 41003183›Full record

ArticleJournal of fungi (Basel, Switzerland)2025

Potential Antioxidant and Neuroprotective Effect of Polysaccharide Isolated from Digüeñe

Claudia Pérez, Fabián A Figueroa, Ignacio Tello, Roberto T Abdala-Díaz, Manuel Marí-Beffa, Viviana Salazar-Vidal, José Becerra, Javiera Gavilán, Jorge Fuentealba

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Claudia PérezLaboratorio de Química de Productos Naturales, Departamento de Botánica, Facultad de Ciencias Naturales y Oceanográficas, Universidad de Concepción, Concepción 4030000, Chile.ORCID 0000-0002-8562-3842
Fabián A FigueroaLaboratorio de Química de Productos Naturales, Departamento de Botánica, Facultad de Ciencias Naturales y Oceanográficas, Universidad de Concepción, Concepción 4030000, Chile.ORCID 0000-0001-9383-8045
Ignacio TelloLaboratorio de Química de Productos Naturales, Departamento de Botánica, Facultad de Ciencias Naturales y Oceanográficas, Universidad de Concepción, Concepción 4030000, Chile.
Roberto T Abdala-DíazDepartamento de Ecología y Geología, Facultad de Ciencias, Universidad de Málaga, E-29071 Málaga, Spain.
Manuel Marí-BeffaInstituto Andaluz de Biotecnología y Desarrollo Azul (IBYDA), Centro Experimental Grice Hutchinson, Universidad de Málaga. Lomas de San Julián, 2, 29004 Málaga, Spain.
Viviana Salazar-VidalLaboratorio de Química de Productos Naturales, Departamento de Botánica, Facultad de Ciencias Naturales y Oceanográficas, Universidad de Concepción, Concepción 4030000, Chile.
José BecerraLaboratorio de Química de Productos Naturales, Departamento de Botánica, Facultad de Ciencias Naturales y Oceanográficas, Universidad de Concepción, Concepción 4030000, Chile.
Javiera GavilánDepartamento de Biología Celular, Genética y Fisiología, Universidad de Málaga, E-29071 Málaga, Spain.
Jorge FuentealbaLaboratory of Screening of Neuroactive Compounds, Department of Physiology, Faculty of Biological Sciences, University of Concepción, Concepción 4030000, Chile.

Funding

Agencia Nacional de Investigación y Desarrollo FONDEF ID23I10099
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a significant global health challenge, further exacerbated by the anticipated increase in prevalence in the coming years. The accumulation of β-amyloid peptide plays a critical role in the onset of AD; however, emerging evidence suggests that soluble oligomers of β-amyloid may primarily drive the neuronal impairments associated with this condition. Additionally, neurodegenerative diseases like AD are linked to oxidative stress and reduced antioxidant capacity in the brain. Natural products, particularly polysaccharides extracted from mushrooms, have garnered interest due to their neuroprotective properties and the potential to enhance the value of natural sources in addressing human diseases. This study examines the antioxidant and neuroprotective properties of polysaccharides derived from

Indexed as

Cyttaria espinosaefungal polysaccharidesneuroprotectionβ-amyloid peptide

Identifiers

PMID41003183
PMCPMC12470887

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.