Evidence map›Paper›PMID 41003728›Full record

ArticleEuropean journal of pediatrics2025

Diagnosis of patent ductus arteriosus by different echocardiographic methods in very preterm infants.

Carlo Dani, Davide Sarcina, Iuri Corsini, Simone Pratesi, Chiara Poggi, Simona Montano, Barbara Loi, Giulia Regiroli, Daniele De Luca

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carlo DaniDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy. carlo.dani@unifi.It.
Davide SarcinaDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Iuri CorsiniDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Simone PratesiDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Chiara PoggiDivision of Neonatology, Careggi University Hospital of Florence, Largo Brambilla 3, Florence, 50134, Italy.
Simona MontanoDivision of Neonatology, Careggi University Hospital of Florence, Largo Brambilla 3, Florence, 50134, Italy.
Barbara LoiDivision of Pediatrics and Neonatal Critical Care, A. Béclère Medical Center, Paris Saclay University Hospitals, Paris, France.
Giulia RegiroliDivision of Pediatrics and Neonatal Critical Care, A. Béclère Medical Center, Paris Saclay University Hospitals, Paris, France.
Daniele De LucaDivision of Pediatrics and Neonatal Critical Care, A. Béclère Medical Center, Paris Saclay University Hospitals, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is no consensus regarding the timing and diagnostic criteria for identifying hemodynamically significant patent ductus arteriosus (hsPDA). Our aim was to evaluate if the use of different diagnostic criteria at different times could be associated with a different incidence of hsPDA in very preterm infants. We studied 41 infants with gestational age < 32 weeks born in neonatal intensive care units (NICU) in Florence, Italy, or in Paris, France. They received the first echocardiography between 24 and 48 h of life and the second between 72 and 84 h to diagnose hsPDA using Florence and Paris criteria and PDA severity score. Concordance of diagnosis between criteria was evaluated with the Cohen unweighted κ statistic. The incidence of hsPDA diagnosed by the Florence (35%) or Paris (34%) criteria or by PDA severity score (35%) was similar. Concordance was substantial between Florence and Paris criteria and between Florence criteria and PDA severity score but was fair between Paris criteria and PDA severity score. Moreover, concordance significantly changed from the first to the second echocardiography. Conclusion: The studied diagnostic criteria showed important variations of concordance when applied at different times. This led to diagnose hsPDA in different patients at different times while leaving the overall percentage of hsPDA unchanged. Our results suggest that more attention should be paid to the choice of diagnostic criteria for individuating hsPDA in very preterm infants.  What is Known: • There is no consensus regarding the timing and diagnostic criteria for individuating hemodynamically significant patent ductus arteriosus (hsPDA) in preterm infant. • This implies large variations in its frequency and management diagnosis between centers. What is New: • This study evaluated for the first time how different diagnostic criteria used at different postnatal times may influence the diagnosis of hsPDA in very preterm infants.

Indexed as

Ductus Arteriosus, PatentEchocardiographyInfant, Premature, DiseasesFemaleGestational AgeHumansInfant, Extremely PrematureInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalMaleSeverity of Illness IndexDiagnosisEchocardiographyPatent ductus arteriosusPreterm infant

Identifiers

PMID41003728
PMCPMC12474585

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.