Evidence map›Paper›PMID 41004088›Full record

ArticleDermatology and therapy2025

Efficacy and Tolerability of a Facial Serum Before and After Ablative Fractional Carbon Dioxide Laser: A Randomized Controlled Trial on Chinese Women.

Jing Li, Xingzuo Liu, Zhiming Zhang, Hequn Wang, Jingbo Ma, Yanwen Jiang, Le Sheng, Shumei Li, Ji Zhang, Xinrong Lin and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dermatology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jing LiL'Oréal Research and Innovation, Shanghai, China.
Xingzuo LiuL'Oréal Research and Innovation, Shanghai, China.
Zhiming ZhangL'Oréal Research and Innovation, Shanghai, China.
Hequn WangL'Oréal Research and Innovation, Clark, NJ, USA.
Jingbo MaDermatology Department, Worldpath Clinic International, Shanghai, China.
Yanwen JiangShanghai China-Norm Quality Technical Service Co., Ltd, Shanghai, China.
Le ShengL'Oréal Research and Innovation, Clark, NJ, USA.
Shumei LiL'Oréal Research and Innovation, Shanghai, China.
Ji ZhangL'Oréal Research and Innovation, Shanghai, China.
Xinrong LinL'Oréal Research and Innovation, Shanghai, China.
Kungchi HsuL'Oréal Research and Innovation, Shanghai, China.
Yidong TuL'Oréal Research and Innovation, Shanghai, China.
Andrew SteelL'Oréal Research and Innovation, Shanghai, China.
Yan WuDermatology Department, Peking University First Hospital, Beijing, China. 3437477565@qq.com.
Frederic FlamentL'Oréal Research and Innovation, Paris, France. frederic.flament@loreal.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAblative fractional CO

methodsThis randomized controlled trial included 72 healthy Chinese women with acne scars who intended to undergo AFCO

resultsTEWL improvement was significantly better in the serum group than in the control group throughout the study (p < 0.001), including pre-treatment (p = 0.043), self-recovery (D15-D31) (p < 0.001), and post-treatment (p = 0.027) stages. In the post-treatment stage, the improvement in skin hydration with the serum was significantly better than in the control group (p < 0.001). The serum group showed significantly better improvements in smoothness (p = 0.001), brightness (p = 0.016), and overall healthy appearance (p = 0.001) compared with controls.

conclusionPeri-AFCO

trial registrationThis trial was retrospectively registered on 30 June 2025: ISRCTN identifier ISRCTN60519611.

Indexed as

Ablative fractional CO2 laserAfter procedureBefore procedureSerumSkin barrier functionSkincare

Identifiers

PMID41004088
PMCPMC12619869

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.