Evidence map›Paper›PMID 41004137›Full record

ReviewBritish medical bulletin2025

PTSD and complex PTSD, current treatments and debates: a review of reviews.

Jo Billings, Helen Nicholls

Abstract readReview
In one paragraph

Review in British medical bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Choreographing time: toward therapy-aligned entactogens for complex PTSD.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jo BillingsDivision of Psychiatry, UCL, Wing A, 4th Floor, 149 Tottenham Court Road, London, W1T 7NF, United Kingdom.ORCID 0000-0003-1238-2440
Helen NichollsDivision of Psychiatry, UCL, Wing A, 4th Floor, 149 Tottenham Court Road, London, W1T 7NF, United Kingdom.ORCID 0000-0001-9334-2285

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe National Institute for Health and Care Excellence guidelines for post-traumatic stress disorder (PTSD) were published in 2018, based on research up until that point. In this review, we summarize the current state of the evidence and discuss the findings of systematic reviews and meta-analyses published between 2019 and 2024. SOURCES OF DATA: We include peer-reviewed systematic reviews and meta-analyses published within the last 5 years. AREAS OF AGREEMENT: Reviews and meta-analyses continue to support the efficacy, and cost-effectiveness, of trauma-focused psychological interventions, particularly Trauma-Focused Cognitive-Behavioural Therapy and Eye Movement Desensitization and Reprocessing. AREAS OF CONTROVERSY: Despite their demonstrated efficacy, dropout rates from psychological interventions for PTSD remain high. There has also been a rapid proliferation of research into novel interventions for treating PTSD. However, much of this research is of low quality and lacks head-to-head comparisons with established interventions. GROWING POINTS: Novel methods of delivery of established treatments are being developed, including using virtual reality, intensive forms of treatment, and digital and remote methods of delivery. AREAS TIMELY FOR DEVELOPING RESEARCH: More qualitative research to explore recipients' experiences of interventions. More good-quality research and head-to-head comparisons of treatments.

Indexed as

Stress Disorders, Post-TraumaticCognitive Behavioral TherapyCost-Benefit AnalysisEye Movement Desensitization ReprocessingHumansCPTSDevidence basePTSDsystematic reviewtreatment

Identifiers

PMID41004137
PMCPMC12466117

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.