ReviewEBioMedicine2025
Broadening dementia risk models: building on the 2024 Lancet Commission report for a more inclusive global framework.
Review in EBioMedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Associations of dementia polyexposure scores to Alzheimer's disease endophenotypes in a diverse population.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Shaping the scientific agenda: Defining and operationalizing brain health in aging.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Outcome-specific risk factors challenge universal dementia prevention priorities: Findings from the Egyptian Dementia Network Registry.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- The exposome of brain aging across 34 countries.Nature medicine · 2026Article
- Sociodemographic differences in dementia prevention knowledge in Germany: Implications for targeted health communication.The journal of prevention of Alzheimer's disease · 2026Article
- Preventing Parkinson's disease in the context of movement disorders: a narrative review of current evidence and future directions.Neurological research and practice · 2026Review
- The principles of Population-Level Approaches to Dementia Risk Reduction (PLADRR).PLoS medicine · 2026Article
- Community-based interventions for cognitive health in older adults: a scoping review.BMC geriatrics · 2026Article
- Precision prevention for neurodegenerative diseases: lessons learnt from Alzheimer's disease translated into perspectives for Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- The Nottingham consensus on dementia risk reduction policy: recommendations from a modified Delphi process.Nature reviews. Neurology · 2026Review
- Advancing brain health equity with Indigenous peoples: A critical imperative.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Accounting for inequality in dementia prevention programmes.Bulletin of the World Health Organization · 2026Article
- Trends in Adult Cochlear Implant Access and Uptake Across Ten Years of Reported Data.Audiology research · 2026Article
- Enhancing Alzheimer's Disease and Related Dementia Burden Projections and Policy Targeting in China-Reply.Health data science · 2026Article
- The Population Neuroscience-Dementia Syndemics Framework to better understand global sex and gender-based risk in low- and middle-income countries.Nature aging · 2026Review
- Computational whole-body-exposome models for global precision brain health.Nature communications · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The 2024 Lancet Commission Report on dementia prevention has identified 14 modifiable risk factors that account for approximately 45% of global dementia cases. We used a global multidimensional approach that integrates gender equity considerations, poverty, wealth shocks, income inequality and HIV infection rates to identify additional risk factors beyond those reported in 2024 report. This methodological framework aims to enhance equitable prevention strategies to mitigate the global burden of dementia. We demonstrate that adding four additional risk factors: poverty, wealth shocks, income inequality, and HIV, while also considering the influences of sex and gender will improve the global applicability of the 2024 report. This is important because, despite dementia primarily affecting women, 57% of the risk factors identified in the 2024 report are more prevalent in men. Our analysis suggests that incorporating these four additional factors could potentially increase the proportion of preventable dementia cases to about 65%. This approach would also reshape the understanding of dementia risk, indicating that around 56% of modifiable risks disproportionately impact women. Expanding risk models in this manner is crucial for developing equitable and effective global dementia prevention strategies, particularly in underrepresented regions. We present these considerations as enhancements to the Commission's significant work.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.