Evidence map›Paper›PMID 41004984›Full record

ArticleCell calcium2025

Neuronal regulation of myenteric interstitial cells of Cajal (ICC-MY) in the proximal colon.

Salah A Baker, Bernard T Drumm, Manushri Karwa, Katy M Thompson, Benjamin Smith, Kenton M Sanders

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell calcium, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Salah A BakerDepartment of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, NV, 89557. Electronic address: sabubaker@med.unr.edu.
Bernard T DrummSmooth Muscle Research Centre, Dundalk Institute of Technology, Dublin Road, Dundalk, A91K584, Ireland.
Manushri KarwaDepartment of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, NV, 89557.
Katy M ThompsonDepartment of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, NV, 89557.
Benjamin SmithDepartment of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, NV, 89557.
Kenton M SandersDepartment of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, NV, 89557. Electronic address: ksanders@med.unr.edu.

Funding

Role of interstitial cells of Cajal in patterned colonic motor activityR01DK120759 · NIDDK · UNIVERSITY OF NEVADA RENO · PI Sal Baker, KENTON M SANDERS · 2019 to 2026
$3.4M
NIDDK NIH HHS R01 DK120759
6 · The paper itself

Abstract

Interstitial cells of Cajal (ICC) generate contractile patterns of colonic motility. We investigated innervation of ICC within the plane of the myenteric plexus (ICC-MY) in proximal colon using mice expressing GCaMP6f in ICC. ICC-MY generated localized Ca

Indexed as

ColonInterstitial Cells of CajalMyenteric PlexusNeuronsAnimalsAnoctamin-1CalciumCalcium SignalingMiceANO1 protein, mouseAnoctamin-1CalciumCa(2+) imagingColonic motilityNeurotransmissionPacemakerPeristalsis

Identifiers

PMID41004984
PMCPMC12684227

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.