ArticleeNeuro2025
Association of 206 Brain Structural Connectivity with Different Types of Strokes: A Mendelian Randomization Study.
Article in eNeuro, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association between brain structural connectivity (BSC) and different subtypes of stroke has not been reported. The current study determined whether some BSC patterns may contribute to the risk of stroke. A two-sample, bidirectional, multivariate Mendelian randomization (MR) analysis was performed. Genome-wide association summary statistics for BSC were obtained from the GWAS Catalog at the European Bioinformatics Institute, while stroke outcome data were obtained from the FinnGen study for intracerebral hemorrhage (ICH) and from the MEGASTROKE Consortium for ischemic stroke (IS) and its subtypes. A colocalization analysis was performed to determine whether the association between BSC and stroke was driven by loci within genomic regions. Reverse MR was performed to evaluate potential stroke-induced changes in BSC. Among the significant findings, left hemisphere (LH) somatomotor network-to-LH salience/ventral attention network white matter (WM) structural connectivity (SC) [OR = 1.30;
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.