Evidence map›Paper›PMID 41006383›Full record

SynthesisScientific reports2025

Antioxidant and anticancer properties of citrus-mediated nanoformulations revealed by meta-analysis.

Rahmat Budiarto, Mohammad Miftakhus Sholikin, Danung Nur Adli, Teguh Wahyono, Temoor Ahmed, Tri Ujilestari, Hayssam M Ali

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rahmat Budiarto *Department of Agronomy, Faculty of Agriculture, Universitas Padjadjaran, Sumedang, 45363, Indonesia. rahmat.budiarto@unpad.ac.id.
Mohammad Miftakhus Sholikin *Research Center for Animal Husbandry, National Research and Innovation Agency (BRIN), Bogor, 16915, Indonesia.
Danung Nur AdliSmart Livestock Industry Study Programme, Department of Feed and Animal Nutrition, Faculty of Animal Science, Universitas Brawijaya, Malang, East Java, 65145, Indonesia.
Teguh WahyonoResearch Center for Food Technology and Processing, National Research and Innovation Agency (BRIN), Gunungkidul, 55861, Indonesia.
Temoor AhmedInstitute of Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Tri UjilestariResearch Center for Animal Husbandry, National Research and Innovation Agency (BRIN), Bogor, 16915, Indonesia.
Hayssam M AliDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, 11421, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to explore and analyse the potential antioxidant and anticancer potential of various citrus-mediated nanoformulations (CMNs), focusing on their effectiveness in scavenging free radicals and inducing cytotoxicity in cancer cells. This research employs a meta-analysis approach to assess data from multiple studies on CMNs. This study is the first meta-analysis to evaluate the antioxidant and anticancer properties of CMNs concurrently. This study offers a novel perspective by examining citrus species, plant parts utilised, nanoparticle types, particle sizes, and coating materials. The analysis employs the Population, Intervention, Comparison, and Outcome (PICO) framework and complies with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The analysis utilizes Hedges' effect size and includes validation through fail-safe N. The IC

Indexed as

Antineoplastic AgentsAntineoplastic Agents, PhytogenicAntioxidantsCitrusNanoparticlesPlant ExtractsHumansNeoplasmsAntineoplastic AgentsAntineoplastic Agents, PhytogenicAntioxidantsPlant ExtractsAntioxidant activityCancer cell cytotoxicityCitrus-mediated nanoformulationsCitrus peel extractSilver nanoparticles

Identifiers

PMID41006383
PMCPMC12475069

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.