ArticlePediatric research2025
Positive association between visceral adiposity index and asthma in US children and adolescents: an analysis of NHANES data.
Article in Pediatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Skeletal Muscle Mass and Visceral Fat are Independently Associated with Poorly Controlled Asthma in Children with Obesity: A Cross-Sectional Study.Journal of asthma and allergy · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAsthma represents an inflammatory condition. The exact function of VAI in asthma among children and adolescents is still not well understood.
methodsA cross-sectional investigation was carried out by utilizing data sourced from 7814 children and adolescents participating in the National Health and Nutrition Examination Survey (NHANES) spanning from 1999 to 2020. It adjusted for covariates and employed techniques such as multivariate logistic regression, restricted cubic spline modeling, and subgroup analyses.
resultsOf the 7814 participants, 1453 (18.6%) had a self-reported asthma diagnosis by a healthcare provider. After multivariate adjustment, higher visceral adiposity index (VAI) quartiles showed a dose-dependent increase in asthma risk compared to the lowest quartile (Q1): OR = 1.06 (Q2), 1.18 (Q3), and 1.26 (Q4; 95% CI: 1.05-1.51, p = 0.014). The restricted cubic spline regression demonstrated linearity. Stratified analyses showed no significant interaction between subgroups.
conclusionsElevated VAI levels are independently linked to a higher prevalence of asthma among US children and adolescents. IMPACT: Key message: Elevated visceral adiposity index (VAI) is independently associated with increased asthma prevalence in US children and adolescents, revealing a dose-dependent relationship. Novelty to literature: This study establishes a nationally representative, large-scale epidemiological link between VAI (a validated biomarker of visceral fat dysfunction) and pediatric asthma using NHANES data (N = 7814). It advances prior obesity-asthma research by quantifying how visceral adiposity-rather than general obesity-drives risk. Clinical/public health impact: Our findings propose VAI as a potential screening tool for asthma risk stratification. This could inform targeted interventions (e.g., metabolic health optimization) to mitigate asthma burden in pediatric populations.
Identifiers
41006885What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.