Evidence map›Paper›PMID 41006954›Full record

ArticleThoracic cancer2025

Trastuzumab Deruxtecan-Induced Myotoxicity: First Case Report About Myopathy in Patient With Normal Body Composition and Clinical Insights.

Zhen Qiao, LiuDan Li, Hong Wang, ShuHui Dai, LiTong Ye

Abstract readCase Reports
In one paragraph

Article in Thoracic cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhen QiaoDepartment of Breast Surgery, Zhuhai Center For Maternal and Child Health Care (Zhuhai Women and Children's Hospital), Zhuhai, China.
LiuDan LiDepartment of Breast Surgery, Zhuhai Center For Maternal and Child Health Care (Zhuhai Women and Children's Hospital), Zhuhai, China.
Hong WangDepartment of Breast Surgery, Zhuhai Center For Maternal and Child Health Care (Zhuhai Women and Children's Hospital), Zhuhai, China.
ShuHui DaiDepartment of Nursing, Zhuhai Center For Maternal and Child Health Care (Zhuhai Women and Children's Hospital), Zhuhai, China.
LiTong YeHospital Infection Control Department, Zhuhai Center For Maternal and Child Health Care (Zhuhai Women and Children's Hospital), Zhuhai, China.

Funding

2023 Zhuhai Medical Research Project 2220009000242Zhuhai Science and Technology Plan Project in the Field of Social Development 2420004000202
6 · The paper itself

Abstract

Trastuzumab deruxtecan (T-DXd) significantly improves outcomes in HER2-positive or low metastatic breast cancer (MBC), but systematic documentation of its myotoxicity is lacking. A 45-year-old woman with HER2-low MBC and normal body composition (BMI 22.9 kg/m

Indexed as

Antineoplastic Agents, ImmunologicalBreast NeoplasmsMuscular DiseasesMyotoxicityTrastuzumabBody CompositionFemaleHumansMiddle AgedAntineoplastic Agents, ImmunologicalTrastuzumabcreatine kinaseglutathionemagnesium isoglycyrrhizinatemyotoxicitytrastuzumab deruxtecan

Identifiers

PMID41006954
PMCPMC12474558

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.