Evidence map›Paper›PMID 41007158›Full record

ReviewBioengineering (Basel, Switzerland)2025

Finite Element Modeling in Left Ventricular Cardiac Biomechanics: From Computational Tool to Clinical Practice.

Patrick Hoang, Julius Guccione

Erratum issuedAbstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Patrick HoangSchool of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-4810-6341
Julius GuccioneDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.

Funding

Software-guided Operative Planning of MitraClip PlacementR44HL169034 · NHLBI · 3DT HOLDINGS, LLC · PI Julius Matteo Guccione, GHASSAN S KASSAB · 2024 to 2026
$2.6M
NHLBI NIH HHS R44 HL169034NIH 4R44HL169034-02.
6 · The paper itself

Abstract

Finite element (FE) modeling has emerged as a powerful computational approach in cardiovascular biomechanics, enabling detailed simulations of myocardial stress, strain, and hemodynamics, which are challenging to measure with conventional imaging techniques. This narrative review explores the progression of cardiac FE modeling from research-focused applications to its increasing integration into clinical practice. Specific attention is given to the mechanical effects of myocardial infarction, the limitations of conventional LV volume-reduction surgeries, and novel therapeutic approaches like passive myocardial reinforcement via hydrogel injections. Furthermore, the review highlights the critical role of patient-specific FE simulations in optimizing LV assist device parameters and guiding targeted device placements. Cutting-edge developments in artificial intelligence-enhanced FE modeling, including surrogate models and precomputed simulation databases, are examined for their potential to facilitate real-time, personalized therapeutic decision-making. Collectively, these advancements position FE modeling as an essential tool in precision medicine for structural heart disease.

Indexed as

artificial intelligencecardiac biomechanicsclinical decision-makingfinite element modelingheart failurehydrogel injectionsLVAD optimizationmachine learningmyocardial infarctionpatient-specific modelingsurgical ventricular restoration (SVR)surrogate modelsventricular remodeling

Identifiers

PMID41007158
PMCPMC12467504

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.