Evidence mapPaperPMID 41007181Full record

ReviewBioengineering (Basel, Switzerland)2025

3D Printing for Tissue Engineering: Printing Techniques, Biomaterials, Challenges, and the Emerging Role of 4D Bioprinting.

Victor M Arias-Peregrino, Aldo Y Tenorio-Barajas, Claudia O Mendoza-Barrera, Jesús Román-Doval, Esteban F Lavariega-Sumano, Sandra P Torres-Arellanes, Ramón Román-Doval

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Victor M Arias-PeregrinoTecnológico Nacional de México/IT de Villahermosa, Carretera Villahermosa-Frontera Km 3.5, Ciudad Industrial, Villahermosa 86010, Tabasco, Mexico.ORCID 0000-0001-5925-4097
Aldo Y Tenorio-BarajasFacultad de Ciencias Físico Matemáticas, Benemérita Universidad Autónoma de Puebla, Puebla 72570, Puebla, Mexico.ORCID 0000-0001-7256-5199
Claudia O Mendoza-BarreraFacultad de Ciencias Físico Matemáticas, Benemérita Universidad Autónoma de Puebla, Puebla 72570, Puebla, Mexico.ORCID 0000-0002-6544-1312
Jesús Román-DovalHospital General de Zona #86, Instituto Mexicano del Seguro Social, Uruapan 60137, Michoacán, Mexico.
Esteban F Lavariega-SumanoTecnológico Nacional de México/IT del Valle de Etla, Santiago Suchilquitongo, Oaxaca 68230, Oaxaca, Mexico.
Sandra P Torres-ArellanesTecnológico Nacional de México/IT del Valle de Etla, Santiago Suchilquitongo, Oaxaca 68230, Oaxaca, Mexico.ORCID 0009-0001-8072-8362
Ramón Román-DovalTecnológico Nacional de México/IT del Valle de Etla, Santiago Suchilquitongo, Oaxaca 68230, Oaxaca, Mexico.ORCID 0000-0003-2495-1719

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organ failure constitutes a significant global concern requiring urgent attention. While organ transplantation offers prospective treatment, it remains suboptimal. The scarcity of donor organs and the need for lifelong immunosuppressive treatments highlight the necessity for innovative approaches in regenerative medicine. In response, tissue engineering has emerged as a promising alternative, particularly through advancements in three-dimensional (3D) and four-dimensional (4D) printing technologies. These approaches enable the fabrication of complex, patient-specific constructs for regenerating tissues such as skin, bone, cartilage, and vascularized organs. This review systematically examines 3D printing techniques, commonly used biomaterials (e.g., hydrogels, bio-inks, and polymers), and their applications in dermal, cardiovascular, bone, and neural regeneration. In addition to discussing 3D technology, an introduction to 4D bioprinting is provided, enabling advanced biomedical applications and establishing itself as an innovative tool that enhances the classic approach to 3D bioprinting in the context of regenerative medicine. Finally, key challenges and ethical considerations are discussed to provide a comprehensive perspective on the current state and future of printed scaffolds in regenerative medicine.

Indexed as

3D printingbioprintingprinting techniquesscaffoldstissue engineering

Identifiers

PMID41007181
PMCPMC12467047

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.