Evidence map›Paper›PMID 41007261›Full record

ArticleBiology2025

Mulberroside A: A Multi-Target Neuroprotective Agent in Alzheimer's Disease via Cholinergic Restoration and PI3K/AKT Pathway Activation.

Jin Li, Jiawen Wang, Yaodong Li, Jingyi Guo, Ziliang Jin, Shourong Qiao, Yunxia Zhang, Guoyin Li, Huazhen Liu, Changjing Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Mulberroside A attenuates HMolecular medicine reports · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jin LiDepartment of Basic Veterinary Medicine, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0001-9878-7523
Jiawen WangInstitute of Translational Medicine, College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou 466001, China.
Yaodong LiInstitute of Translational Medicine, College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou 466001, China.
Jingyi GuoInstitute of Translational Medicine, College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou 466001, China.
Ziliang JinInstitute of Translational Medicine, College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou 466001, China.
Shourong QiaoInstitute of Translational Medicine, College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou 466001, China.
Yunxia ZhangInstitute of Translational Medicine, College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou 466001, China.ORCID 0000-0002-6680-5632
Guoyin LiInstitute of Translational Medicine, College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou 466001, China.
Huazhen LiuDepartment of Basic Veterinary Medicine, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0003-1699-8760
Changjing WuInstitute of Translational Medicine, College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou 466001, China.ORCID 0000-0001-9196-8532

Funding

College Student Innovation and Entrepreneurship Training Program Project (202410478005)Henan Provincial Science and Technology Key Project (242102310430)
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia, with current therapies offering only limited symptomatic relief and lacking disease-modifying efficacy. Addressing this critical therapeutic gap, natural multi-target compounds like mulberroside A (MsA)-a bioactive glycoside from

Indexed as

Alzheimer’s diseasecholinergic systemcognitive impairmentMulberroside AneuroprotectionPI3K/AKT signaling

Identifiers

PMID41007261
PMCPMC12467343

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.