Evidence map›Paper›PMID 41007373›Full record

ArticleBiology2025

Dysregulation of Protein Kinase CaMKI Leads to Autism-Related Phenotypes in Synaptic Connectivity, Sleep, Sociality, and Aging-Dependent Degeneration in

Claudia Gualtieri, Zachary M Smith, Abby Cruz, Ziam Khan, Conor Jenkins, Ketu Mishra-Gorur, Fernando J Vonhoff

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Claudia GualtieriDepartment of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA.
Zachary M SmithDepartment of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA.ORCID 0000-0003-2271-1412
Abby CruzDepartment of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA.
Ziam KhanDepartment of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA.ORCID 0000-0002-5134-6832
Conor JenkinsDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Ketu Mishra-GorurDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510, USA.
Fernando J VonhoffDepartment of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA.ORCID 0000-0002-0679-1857

Funding

U-RISE at University of Maryland Baltimore CountyT34GM136497 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI PHYLLIS R ROBINSON · 2020 to 2026
$9.5M
National Science Foundation Award #1002566NIGMS NIH HHS T34 GM136497NIGMS NIH HHS T34GM136497
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) encompasses a range of conditions, primarily marked by deficits in social behaviors, along with several comorbidities such as sleep abnormalities and motor dysfunction. Recent studies have identified genetic risk factors associated with ASD, including the

Indexed as

activity-dependentautism spectrum disorderchemorepulsioncircadian rhythminvertebratelocomotionneurodegenerativeneurodevelopmentproteomicssynaptic pruning

Identifiers

PMID41007373
PMCPMC12467204

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.