Evidence map›Paper›PMID 41007772›Full record

ArticleBiomedicines2025

Genomic and Structural Investigation of Mutations in Biotinidase (BTD) Gene Deficiency in Greater Middle Eastern Cohort: Insights from Molecular Dynamics Study.

Faisal E Ibrahim, BalaSubramani Gattu Linga, Muthanna Samara, Jameela Roshanuddin, Salma Younes, Gheyath K Nasrallah, Hatem Zayed, M Walid Qoronfleh, Sawsan G A A Mohammed, Dalia El Khoury and 4 more

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Faisal E IbrahimDepartment of Research, Women's Wellness and Research Center, Hamad Medical Corporation (HMC), P.O. Box 3050, Doha 0974, Qatar.ORCID 0009-0004-0431-5744
BalaSubramani Gattu LingaDepartment of Research, Women's Wellness and Research Center, Hamad Medical Corporation (HMC), P.O. Box 3050, Doha 0974, Qatar.ORCID 0009-0003-8814-7399
Muthanna SamaraDepartment of Psychology, Kingston University London, Penrhyn Road, London KT1 2EE, UK.ORCID 0000-0002-7857-1204
Jameela RoshanuddinDepartment of Research, Women's Wellness and Research Center, Hamad Medical Corporation (HMC), P.O. Box 3050, Doha 0974, Qatar.ORCID 0009-0000-7709-5229
Salma YounesDepartment of Biomedical Science, College of Health Sciences, Member of QU Health, Qatar University, Doha 2713, Qatar.
Gheyath K NasrallahDepartment of Biomedical Science, College of Health Sciences, Member of QU Health, Qatar University, Doha 2713, Qatar.ORCID 0000-0001-9252-1038
Hatem ZayedDepartment of Biomedical Science, College of Health Sciences, Member of QU Health, Qatar University, Doha 2713, Qatar.ORCID 0000-0001-8838-6638
M Walid QoronflehHealthcare Research & Policy Division, Q3 Research Institute (QRI), Ann Arbor, MI 48197, USA.ORCID 0000-0001-6757-1922
Sawsan G A A MohammedQU Health, College of Medicine, Qatar University, Doha 2713, Qatar.
Dalia El KhouryDepartment of Family Relations and Applied Nutrition, University of Guelph, 50 Stone Road East, Guelph, ON N1G2W1, Canada.
Dinesh VelayuthamLiberal Arts and Science (LAS), Hamad Bin Khalifa University (HBKU), P.O. Box 34110, Doha 34110, Qatar.ORCID 0000-0002-9425-7266
Ghassan AbdohDepartment of Neonatology, Neonatal Intensive Care Unit (NICU), Newborn Screening Unit, Women's Wellness and Research Center (WWRC), Hamad Medical Corporation (HMC), Doha 3050, Qatar.
Hilal Al RifaiGenomics and Precision Medicine (GPM), College of Health & Life Science (CHLS), Hamad Bin Khalifa University (HBKU), Doha 34110, Qatar.
Nader Al-DewikDepartment of Research, Women's Wellness and Research Center, Hamad Medical Corporation (HMC), P.O. Box 3050, Doha 0974, Qatar.ORCID 0000-0001-5739-1135

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biotinidase deficiencygenotype–phenotype correlationmolecular dynamicsprotein stabilityQatar Genome Programsingle-nucleotide polymorphism

Identifiers

PMID41007772
PMCPMC12467526

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.