Evidence map›Paper›PMID 41007839›Full record

ArticleBiomedicines2025

Valemetostat-SAHA-Driven Acetylation of p53 via SET/TAF-Iβ Displacement and p300 Activation Modulates Cell Cycle Regulators in Pancreatic Cancer Cells.

Michele Di Crosta, Francesca Chiara Ragone, Rossella Benedetti, Gabriella D'Orazi, Roberta Santarelli, Maria Saveria Gilardini Montani, Mara Cirone

Erratum issuedAbstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Vorinostat Potentiates Chemoimmunotherapy in Immune-Enriched Pancreatic Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Michele Di CrostaDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0009-0007-4085-8350
Francesca Chiara RagoneDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Rossella BenedettiDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-1825-9112
Gabriella D'OraziFaculty of Medicine, UniCamillus-Saint Camillus International University of Health and Medical Sciences, 00131 Rome, Italy.ORCID 0000-0001-6876-9105
Roberta SantarelliDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-9416-7594
Maria Saveria Gilardini MontaniDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-8722-7539
Mara CironeDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-2207-9624

Funding

Italian Association for Cancer Research IG 2019 Id.23040Ministero dell'università e della ricerca PRIN 2022
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acetylationCHK1mutp53p21p300pancreatic cancerSET/TAF-Iβ

Identifiers

PMID41007839
PMCPMC12467070

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.