Evidence map›Paper›PMID 41007891›Full record

ReviewAnimals : an open access journal from MDPI2025

Platelet-Rich Plasma in Equine Osteoarthritis: A Systematic Review of Clinical and Experimental Evidence.

Jorge U Carmona, Catalina López

Abstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jorge U CarmonaGrupo de Investigación Terapia Regenerativa, Departamento de Salud Animal, Universidad de Caldas, Calle 65 No 26-10, Manizales 170004, Colombia.ORCID 0000-0002-6917-8451
Catalina LópezGrupo de Investigación Patología Clínica Veterinaria, Departamento de Salud Animal, Universidad de Caldas, Calle 65 No 26-10, Manizales 170004, Colombia.ORCID 0000-0003-4954-1601

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is a major cause of equine lameness, with few effective disease-modifying treatments. This systematic review, conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, evaluated the efficacy of platelet-rich plasma (PRP) for equine OA by analyzing 11 studies (6 clinical, 5 experimental) identified through Web of Science, Scopus, and PubMed (2000-2024). The screening process identified 252 records, of which 136 were duplicates and 105 were excluded based on predefined criteria. The analysis showed that intra-articular PRP injections are generally safe, with transient synovial inflammation occurring mainly when PRP was activated with bovine thrombin. Both leukocyte-rich (L-PRP) and leukocyte-poor (P-PRP) formulations exhibited comparable efficacy, though optimal platelet concentrations (423-658 × 10

Indexed as

equine osteoarthritisintra-articular treatmentsorthobiologicsplatelet-rich plasmaregenerative medicine

Identifiers

PMID41007891
PMCPMC12466402

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.