ArticleAnimals : an open access journal from MDPI2025
Housing in a Large Open Cage Did Not Affect the Phenotypic Traits of Obese Male Zucker fa/fa Rats When Compared to IVC-Housed Rats, but Improved the Rats' Well-Being.
Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
The housing of laboratory rats in cages with dimensions according to international standards for research animals can hardly be regarded as a stimulating environment, even when fulfilling the minimum requirements for environmental enrichment. Little is known about whether changes in the housing situations to improve living conditions will affect the phenotypic traits of well-known models for human diseases. The obese Zucker fa/fa rat develops hyperlipidemia, hypertension, and fatty liver, and is widely used for studies on metabolic complications of obesity in humans. Young male obese Zucker fa/fa rats were housed in pairs in standard individually ventilated cages (IVCs: floor area 1500 cm
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