ArticleFoods (Basel, Switzerland)2025
Development and Characterization of Spray-Dried Curcumin-Lecithin Complexes with Improved Solubility and In Vitro Digestive and Thermal Stability.
Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Post-thaw quality of donkey (Equus asinus) spermatozoa exposed to different concentrations of curcumin with respect to oxidative status and nitric oxide.Veterinary research communications · 2026Review
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Authors and funding
3 authors.
Funding
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Abstract
Curcumin, a bioactive polyphenol from turmeric, faces significant challenges in food and pharmaceutical applications due to its poor water solubility, low stability, and limited bioavailability. In this study, curcumin-lecithin complexes (phytosomes) were spray-dried using maltodextrin as the carrier polymer to produce free-flowing powders with improved physicochemical properties. The powders were characterized based on moisture content, particle size, morphology, curcumin loading, thermal behavior, and stability under simulated gastrointestinal and thermal conditions. The lecithin-curcumin complexes exhibited high entrapment efficiency (up to 94%), a predominantly amorphous structure, and improved thermal and digestive stability compared to free curcumin. Particle size and wettability were influenced by carrier and curcumin ratios, with maltodextrin enhancing powder flowability and apparent solubility. Morphological analyses revealed spherical particles with core-shell structures, confirming successful complexation. The complexes protected curcumin from degradation at intestinal pH and elevated temperatures, highlighting their potential for enhanced bioavailability. These findings demonstrate that spray-dried curcumin-lecithin complexes with maltodextrin carriers offer a promising strategy to overcome curcumin's solubility and stability limitations, supporting their application in functional foods and pharmaceuticals.
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Registered trials
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