Evidence map›Paper›PMID 41008859›Full record

ArticleCancers2025

Minimally Invasive Distal Pancreatectomy as the Standard of Care in the US: Are We There Yet?

Laleh Foroutani, Andrew Gonzalez, Jaeyun Jane Wang, Bahaa I Aburayya, Amir Ashraf Ganjouei, Jean Feng, Lucas Willian Thornblade, Kenzo Hirose, Ajay V Maker, Eric Nakakura and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Laleh ForoutaniDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Andrew GonzalezDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Jaeyun Jane WangDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-3705-3993
Bahaa I AburayyaFaculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0009-0002-4177-2288
Amir Ashraf GanjoueiDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Jean FengDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA 94158, USA.ORCID 0000-0003-2041-3104
Lucas Willian ThornbladeDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Kenzo HiroseDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Ajay V MakerDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Eric NakakuraDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Carlos Uriel CorveraDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Adnan AlseidiDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Mohamed A AdamDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWhile there is an increasing shift towards minimally invasive distal pancreatectomy (MIDP), little is known about how utilization of MIDP vs. open distal pancreatectomy (ODP) has evolved over time. We aimed to determine competing temporal trends in use and outcomes of MIDP (laparoscopic and robotic) over time and to determine if a threshold of effectiveness has been reached.

methodsAdults undergoing MIDP and ODP were identified from the National Cancer Database (2010-2021) and the National Surgical Quality Improvement Program database (2014-2022). Propensity score matching (PSM) was performed to address baseline differences between groups before comparing outcomes. Joinpoint regression analysis (JRA) was employed to assess adjusted trends in adoption and outcomes. We calculated Annual Percentage Change (APC) and Average Annual Percentage Change (AAPC) to quantify yearly adoption rates and their trends, respectively.

resultsAmong 21,966 patients in the NCDB cohort, 49.5% underwent MIDP, including 33.7% laparoscopic distal pancreatectomy (LDP) and 15.8% robotic distal pancreatectomy (RDP), while 50.5% underwent ODP. ODP declined from 74.1% of cases (2010) to 41.1% (2021), with an AAPC of -4.9%. MIDP increased significantly throughout the study from 25.9% of cases (2010) to 58.9% (2021), with an AAPC of 6.3%. Among MIDP subgroups, there was an initial increase in LDP until 2016, after which its rate of utilization stagnated with an AAPC of 0.7% (

conclusionsOver the past decade, the use of MIDP increased while ODP decreased. This increase was initially driven by greater use of LDP, which plateaued after 2016, and was further driven by the increased use of the robotic approach. Specifically, RDP demonstrated consistent growth, while LDP showed a decline around 2016. These findings highlight changing practice patterns, accompanied by improvements across all surgical approaches. This may provide insights for clinical training and resource allocation.

Indexed as

distal pancreatectomyjoinpoint regressionlaparoscopic distal pancreatectomyminimally invasive surgeryopen distal pancreatectomypostoperative pancreatic fistularobotic distal pancreatectomysurgical trends

Identifiers

PMID41008859
PMCPMC12468204

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.