Evidence map›Paper›PMID 41008982›Full record

ReviewAntioxidants (Basel, Switzerland)2025

SIRT1-Mediated Redox and Senescence Regulation in Cancer: Mechanisms and Therapeutic Implications.

Yejin Son, Minyeong Han, Xuefeng Wu, Yoon-Seok Roh

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yejin SonCollege of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.
Minyeong HanCollege of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.
Xuefeng WuDepartment of Immunology and Microbiology, Shanghai Institute of Immunology, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China.ORCID 0000-0002-6933-7280
Yoon-Seok RohCollege of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.ORCID 0000-0003-2512-5857

Funding

Chungbuk National University BK21 Program (2023)National Research of Foundation of Korea RS-2025-00556031National Research of Foundation of Korea RS-2025-02273102National Research of Foundation of Korea RS-2025-02603096Regional Innovation System & Education (RISE) program of Chungbuk 2025-RISE-11-014-03
6 · The paper itself

Abstract

Silent information regulator type 1 (SIRT1), a NAD

Indexed as

cancer therapycellular senescencereactive oxygen speciesredox signalingSIRT1

Identifiers

PMID41008982
PMCPMC12466425

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.