Evidence map›Paper›PMID 41009407›Full record

ArticleInternational journal of molecular sciences2025

Molecular Consequences of

Gulipek Guven Tasbicen, Ali Tufan, Batuhan Savsar, Alper Bulbul, Zeynep Tonbul, Elif Guzel, Dilay Hazal Ayhan, Ahmet Can Timucin, Umut Inci Onat, Gunseli Bayram Akcapinar and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gulipek Guven TasbicenDepartment of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.ORCID 0000-0003-0796-5502
Ali TufanDepartment of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.ORCID 0009-0005-3416-8586
Batuhan SavsarDepartment of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.
Alper BulbulDepartment of Biostatistics and Bioinformatics, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.ORCID 0000-0001-5359-4357
Zeynep TonbulDepartment of Molecular Biology and Genetics, Institute of Natural and Applied Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.ORCID 0000-0002-3448-4395
Elif GuzelDepartment of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.ORCID 0009-0006-4864-7403
Dilay Hazal AyhanDepartment of Molecular Biology and Genetics, Institute of Natural and Applied Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.ORCID 0000-0002-0497-3294
Ahmet Can TimucinDepartment of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.ORCID 0000-0002-9483-3593
Umut Inci OnatDepartment of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.ORCID 0000-0003-4360-9310
Gunseli Bayram AkcapinarDepartment of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.
Ozlem Akgun DoganDepartment of Pediatrics, Division of Pediatric Genetics, School of Medicine, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.ORCID 0000-0002-8310-4053
Yasemin AlanayDepartment of Pediatrics, Division of Pediatric Genetics, School of Medicine, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.
Eda Tahir TuranliDepartment of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.

Funding

Acıbadem University 2024-2170Scientific and Technological Research Council of Turkey 222S011
6 · The paper itself

Abstract

Progressive pseudorheumatoid dysplasia (PPD) is a rare autosomal recessive cartilage disorder caused by biallelic variants in

Indexed as

Arthropathy, NeurogenicCCN Intercellular Signaling ProteinsJoint DiseasesChondrocytesEndoplasmic Reticulum StressExtracellular MatrixHumansReactive Oxygen SpeciesCCN6 protein, humanCCN Intercellular Signaling ProteinsReactive Oxygen Speciescellular communication network factor 6 (CCN6)endoplasmic reticulum stressprogressive pseudorheumatoid dysplasiaWNT1-inducible signaling pathway protein 3

Identifiers

PMID41009407
PMCPMC12469775

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.