Evidence mapPaperPMID 41009443Full record

ArticleInternational journal of molecular sciences2025

Deciphering the Mechanisms Underlying the Antitumor Effects of Eucalyptus Essential Oil and Its Component 3-Cyclohexene-1-Methanol Against Human Colon Cancer Cells.

Sonia Ben Hamouda, Ons Zakraoui, Sonia Souissi, Rania Bouzeyen, Makram Essafi, Khadija Essafi-Benkhadir

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sonia Ben HamoudaInstitut Pasteur de Tunis, LR16IPT04 Laboratoire d'Epidémiologie Moléculaire et Pathologie Expérimentale, Université de Tunis El Manar, Tunis 1002, Tunisia.
Ons ZakraouiInstitut Pasteur de Tunis, LR16IPT04 Laboratoire d'Epidémiologie Moléculaire et Pathologie Expérimentale, Université de Tunis El Manar, Tunis 1002, Tunisia.
Sonia SouissiInstitut Pasteur de Tunis, LR16IPT04 Laboratoire d'Epidémiologie Moléculaire et Pathologie Expérimentale, Université de Tunis El Manar, Tunis 1002, Tunisia.ORCID 0009-0005-2733-5833
Rania BouzeyenInstitut Pasteur de Tunis, LR16IPT02 Laboratoire Transmission, Contrôle et Immunobiologie des Infections, Université de Tunis El Manar, Tunis 1002, Tunisia.
Makram EssafiInstitut Pasteur de Tunis, LR16IPT02 Laboratoire Transmission, Contrôle et Immunobiologie des Infections, Université de Tunis El Manar, Tunis 1002, Tunisia.
Khadija Essafi-BenkhadirInstitut Pasteur de Tunis, LR16IPT04 Laboratoire d'Epidémiologie Moléculaire et Pathologie Expérimentale, Université de Tunis El Manar, Tunis 1002, Tunisia.ORCID 0000-0003-1371-1963

Funding

The Tunisian Ministry of Higher Education and Scientific Research LR16IPT04
6 · The paper itself

Abstract

The development of non-toxic, novel anti-tumor alternatives that target key hallmark events of tumor progression is of a high priority for cancer therapy. Natural compounds, such as Essential oils (EOs) derived from plant extracts are a mixture of chemical components known for their diverse pharmacological properties, including anticancer potential. For this purpose, we investigated the antitumor activity of

Indexed as

Antineoplastic AgentsAntineoplastic Agents, PhytogenicColonic NeoplasmsCyclohexenesEucalyptusOils, VolatileApoptosisCell Cycle CheckpointsCell Line, TumorCell ProliferationCell SurvivalCyclohexane MonoterpenesHumansMAP Kinase Signaling SystemMonoterpenesProto-Oncogene Proteins c-aktAntineoplastic AgentsAntineoplastic Agents, PhytogenicCyclohexane MonoterpenesCyclohexenesMonoterpenesOils, VolatileProto-Oncogene Proteins c-aktanti-tumorbioactive compoundscellular effectorscolon canceressential oilEucalyptus

Identifiers

PMID41009443
PMCPMC12469830

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.