Evidence map›Paper›PMID 41009542›Full record

ArticleInternational journal of molecular sciences2025

New Derivatives of 2-(Cyclohexylamino)thiazol-4(5

Szymon Baumgart, Daria Kupczyk, Anita Płazińska, Oliwia Koszła, Przemysław Sołek, Aneta Archała, Wojciech Płaziński, Renata Studzińska

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Szymon BaumgartDepartment of Organic Chemistry, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 2 Jurasza Str., 85-089 Bydgoszcz, Poland.
Daria KupczykDepartment of Medical Biology and Biochemistry, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 24 Karłowicza Str., 85-092 Bydgoszcz, Poland.ORCID 0000-0003-1542-0879
Anita PłazińskaDepartment of Biopharmacy, Medical University of Lublin, 4a Chodźki Str., 20-093 Lublin, Poland.ORCID 0000-0002-3698-2574
Oliwia KoszłaDepartment of Biopharmacy, Medical University of Lublin, 4a Chodźki Str., 20-093 Lublin, Poland.ORCID 0000-0003-2160-9424
Przemysław SołekDepartment of Biopharmacy, Medical University of Lublin, 4a Chodźki Str., 20-093 Lublin, Poland.ORCID 0000-0002-6194-0042
Aneta ArchałaDepartment of Biopharmacy, Medical University of Lublin, 4a Chodźki Str., 20-093 Lublin, Poland.ORCID 0000-0003-4244-4382
Wojciech PłazińskiDepartment of Biopharmacy, Medical University of Lublin, 4a Chodźki Str., 20-093 Lublin, Poland.ORCID 0000-0003-1427-8188
Renata StudzińskaDepartment of Organic Chemistry, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 2 Jurasza Str., 85-089 Bydgoszcz, Poland.ORCID 0000-0001-5853-4214

Funding

Nicolaus Copernicus University Debuts 7
6 · The paper itself

Abstract

In the present study, we synthesized nine new derivatives of 2-(cyclohexylamino)thiazol-4(5

Indexed as

11-beta-Hydroxysteroid Dehydrogenase Type 1Antineoplastic AgentsEnzyme InhibitorsThiazolesCell Line, TumorCell ProliferationHumansOxidation-ReductionReactive Oxygen Species11-beta-Hydroxysteroid Dehydrogenase Type 1Antineoplastic AgentsEnzyme InhibitorsReactive Oxygen SpeciesThiazoles11β-hydroxysteroid dehydrogenase 12-aminothiazol-4(5H)-one derivativescancer cell metabolic activitycortisolmolecular docking

Identifiers

PMID41009542
PMCPMC12470129

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.