Evidence map›Paper›PMID 41009738›Full record

ArticleInternational journal of molecular sciences2025

Novel Polycaprolactone Based Coating for Catheters: Sustained Antibiotic Release for Enhanced Infection Prevention.

Kyungmi Kim, Eung Hwi Kim, Seung Zhoo Yoon, Suk Joong Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kyungmi KimDepartment of Anesthesiology and Pain Medicine, Anam Hospital, College of Medicine, Korea University, Seoul 02841, Republic of Korea.ORCID 0000-0003-2833-1912
Eung Hwi KimInstitute for Healthcare Service Innovation, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Seung Zhoo YoonDepartment of Anesthesiology and Pain Medicine, Anam Hospital, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Suk Joong LeeDepartment of Chemistry, Korea University, Seoul 02841, Republic of Korea.ORCID 0000-0003-1387-5714

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Healthcare-associated infections are a serious concern, particularly in patients with intravascular catheters. In this study, we developed a novel ampicillin-loaded polycaprolactone (PCL)-coated polyurethane catheter (PUC) wherein polymethylhydrosiloxane (PMHS) enhanced the adhesion between PCL and PUC, ensuring coating durability. PUC were first treated with PMHS, followed by PCL coatings containing 1, 3, or 6 wt% ampicillin. Antibacterial activity against

Indexed as

Anti-Bacterial AgentsCatheter-Related InfectionsCathetersCoated Materials, BiocompatiblePolyestersAmpicillinDelayed-Action PreparationsDrug LiberationEscherichia coliHumansListeriaMicrobial Sensitivity TestsPolyurethanesAmpicillinAnti-Bacterial AgentsCoated Materials, BiocompatibleDelayed-Action PreparationspolycaprolactonePolyestersPolyurethanesampicillinantibacterial coatingbiodegradabilitycatheter-related infectionsmedical devicespolycaprolactonepolymethylhydrosiloxanesustained release

Identifiers

PMID41009738
PMCPMC12470714

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.