Evidence map›Paper›PMID 41009856›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Hybrid 2-Quinolone-1,2,3-triazole Compounds: Rational Design, In Silico Optimization, Synthesis, Characterization, and Antibacterial Evaluation.

Ayoub El-Mrabet, Abderrahim Diane, Rachid Haloui, Hanae El Monfalouti, Ashwag S Alanazi, Mohamed Hefnawy, Mohammed M Alanazi, Youssef Kandri-Rodi, Souad Elkhattabi, Ahmed Mazzah and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ayoub El-MrabetLaboratory of Applied Organic Chemistry, Faculty of Sciences and Techniques, Sidi Mohamed Ben Abdellah University, Route d'Imouzzer, P.O. Box 2202, Fez 30000, Morocco.ORCID 0009-0005-2564-3058
Abderrahim DianeLaboratory of Applied Organic Chemistry, Faculty of Sciences and Techniques, Sidi Mohamed Ben Abdellah University, Route d'Imouzzer, P.O. Box 2202, Fez 30000, Morocco.
Rachid HalouiLaboratory of Engineering, Systems and Applications, National School of Applied Sciences, Sidi Mohamed Ben Abdellah-Fez University, P.O. Box 2202, Fez 30040, Morocco.
Hanae El MonfaloutiLaboratory of Plant Chemistry, Faculty of Sciences, Mohammed V University in Rabat, 4 Avenue 9 Ibn Battouta, P.O. Box 1014, Rabat 10000, Morocco.ORCID 0000-0002-5192-9034
Ashwag S AlanaziDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.ORCID 0000-0003-1042-8126
Mohamed HefnawyDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Mohammed M AlanaziDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-0483-8113
Youssef Kandri-RodiLaboratory of Applied Organic Chemistry, Faculty of Sciences and Techniques, Sidi Mohamed Ben Abdellah University, Route d'Imouzzer, P.O. Box 2202, Fez 30000, Morocco.
Souad ElkhattabiLaboratory of Engineering, Systems and Applications, National School of Applied Sciences, Sidi Mohamed Ben Abdellah-Fez University, P.O. Box 2202, Fez 30040, Morocco.
Ahmed MazzahUniversity of Lille, CNRS, UAR 3290, MSAP, Miniaturization for Synthesis, Analysis and Proteomics, 59000 Lille, France.ORCID 0000-0002-6945-1884
Amal HaoudiLaboratory of Applied Organic Chemistry, Faculty of Sciences and Techniques, Sidi Mohamed Ben Abdellah University, Route d'Imouzzer, P.O. Box 2202, Fez 30000, Morocco.
Nada Kheira SebbarLaboratory of Heterocyclic Organic Chemistry, Pharmacochemistry Competence Center, Faculty of Sciences, Mohammed V University in Rabat, 4 Avenue 9 Ibn Battouta, P.O. Box 1014, Rabat 10000, Morocco.

Funding

Princess Nourah bint Abdulrahman University, Princess Nourah bint Abdulrahman University and King Saud University PNURSP2025R342 and RSPD2025R754
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

1,2,3-triazole2-quinoloneantibacterial activityantibiotic resistancedrug discoveryhybrid moleculesmolecular dockingQSAR modeling

Identifiers

PMID41009856
PMCPMC12466386

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.