Evidence map›Paper›PMID 41009976›Full record

ReviewGenes2025

Genetics of Retinoblastoma: An Overview and Significance of Genetic Testing in Clinical Practice.

Khaled K Abu-Amero, Altaf A Kondkar, Naif A M Almontashiri, Abdullah M Khan, Azza M Y Maktabi, Syed Hameed, Saleh AlMesfer

Abstract readReview
In one paragraph

Review in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Khaled K Abu-AmeroResearch Department, King Khaled Eye Specialist Hospital and Research Center, Riyadh 11462, Saudi Arabia.
Altaf A KondkarGlaucoma Research Chair, Department of Ophthalmology, College of Medicine, King Saud University, Riyadh 11411, Saudi Arabia.ORCID 0000-0002-5516-6951
Naif A M AlmontashiriResearch Department, King Khaled Eye Specialist Hospital and Research Center, Riyadh 11462, Saudi Arabia.ORCID 0000-0003-3607-395X
Abdullah M KhanPediatric Ophthalmology and Strabismus Division and Ocular Oncology Division, King Khaled Eye Specialist Hospital and Research Center, Riyadh 11462, Saudi Arabia.ORCID 0000-0003-1125-7891
Azza M Y MaktabiDepartment of Pathology and Laboratory Medicine and Ocular Oncology Division, King Khaled Eye Specialist Hospital and Research Center, Riyadh 11462, Saudi Arabia.
Syed HameedResearch Department, King Khaled Eye Specialist Hospital and Research Center, Riyadh 11462, Saudi Arabia.ORCID 0009-0004-2746-0784
Saleh AlMesferPediatric Ophthalmology and Strabismus Division and Ocular Oncology Division, King Khaled Eye Specialist Hospital and Research Center, Riyadh 11462, Saudi Arabia.

Funding

King Khaled Eye Specialist Hospital N/A
6 · The paper itself

Abstract

Retinoblastoma is a rare but malignant pediatric retinal tumor, affecting 1 in 15,000-20,000 live births annually. It arises from biallelic mutations in the

Indexed as

Genetic TestingRetinal NeoplasmsRetinoblastomaRetinoblastoma Binding ProteinsGenetic Predisposition to DiseaseGerm-Line MutationHumansMutationUbiquitin-Protein LigasesRB1 protein, humanRetinoblastoma Binding ProteinsUbiquitin-Protein Ligasesclinical geneticsgenetic counselinggenetic testingmolecular diagnosisretinoblastoma

Identifiers

PMID41009976
PMCPMC12469762

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.