Evidence map›Paper›PMID 41010333›Full record

ArticleLife (Basel, Switzerland)2025

Therapeutic Effects of Photobiomodulation Combined with Exercise on Patients with Peripheral Artery Disease Plus Diabetic Foot Ulcer: A Pilot and Feasibility Study.

Shang-Zhen Chen, Tetsuya Takahashi, Hei-Jeng Lai, Hsi-Hsun Su, Yu-Jung Cheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shang-Zhen ChenDivision of Physical Therapy, Department of Physical Medicine and Rehabilitation, Ministry of Health and Welfare Feng Yuan Hospital, Taichung 42055, Taiwan.
Tetsuya TakahashiFaculty of Health Science, Juntendo University, Tokyo 113-0033, Japan.
Hei-Jeng LaiDivision of Physical Therapy, Department of Physical Medicine and Rehabilitation, Ministry of Health and Welfare Feng Yuan Hospital, Taichung 42055, Taiwan.
Hsi-Hsun SuDivision of Physical Therapy, Department of Physical Medicine and Rehabilitation, Ministry of Health and Welfare Feng Yuan Hospital, Taichung 42055, Taiwan.
Yu-Jung ChengDepartment of Physical Therapy, Graduate Institute of Rehabilitation Science, China Medical University, Taichung 406040, Taiwan.

Funding

China Medical University CMU112-MF-90Ministry of Science and Technology of Taiwan MOST 108-2410-H-039-009-MY2
6 · The paper itself

Abstract

backgroundDiabetic foot ulcers (DFUs) in patients with peripheral artery disease (PAD) are difficult to treat and associated with poor healing outcomes. Photobiomodulation therapy (PBMT) and exercise have shown individual benefits, but evidence on their combined effects is limited.

objectiveTo evaluate whether PBMT combined with resistance exercise improves wound healing and walking ability in patients with DFU and PAD.

methodsIn this pilot randomized trial, 11 patients with DFU and PAD were allocated to either PBMT plus supervised exercise or exercise alone for 4 weeks. Outcome measures included wound size, skin temperature, and 6-min walking distance.

resultsPBMT combined with exercise improved wound healing and walking capacity compared with baseline; however, no significant between-group differences were observed. A positive correlation was observed between post-PBMT plantar skin temperature and percentage of wound reduction.

conclusionsPBMT combined with resistance exercise may enhance wound healing and functional mobility in patients with DFU and PAD.

Indexed as

diabetic foot ulcersexerciseperipheral artery diseasephotobiomodulation therapy

Identifiers

PMID41010333
PMCPMC12471431

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.