Evidence map›Paper›PMID 41010491›Full record

Trial reportNutrients2025

Effects of

Biaoxu Tao, Weihao Lian, Rongrong Min, Xiaoyu Zhang, Liqi Chen, Sun Hao, Ze Li, Chengzhe Ma, Haojie Zhang, Chang Liu

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07546513 (Effects of Cistanche Supplementation on Anaerobic Exercise Performance and Recovery in Men With Different Athletic Training Levels), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07546513 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Cistanche Supplementation on Anaerobic Exercise Performance and Recovery in Men With Different Athletic Training Levels: A Double-Blind, Randomized, Placebo-Controlled Trial

TypeinterventionalSponsorBeijing Sport UniversityRan2026 to 2026Enrolled56ConditionsAthlete, Elite Athlete, Sport Performance, Exercise RecoveryArmsCistanche deserticola, Matched placebo paste, Standardized anaerobic training program
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Biaoxu TaoSchool of Sports Training, Wuhan Sports University, Wuhan 430079, China.
Weihao LianCollege of Physical Education, Zhengzhou University, Zhengzhou 450001, China.
Rongrong MinSchool of Sports Training, Wuhan Sports University, Wuhan 430079, China.
Xiaoyu ZhangSchool of Sports Training, Wuhan Sports University, Wuhan 430079, China.
Liqi ChenSchool of Sport Science, Beijing Sport University, Beijing 100084, China.
Sun HaoSchool of Sports Training, Wuhan Sports University, Wuhan 430079, China.
Ze LiSchool of Sport Science, Beijing Sport University, Beijing 100084, China.
Chengzhe MaFaculty of Education, University of Macau, Macao 999078, China.
Haojie ZhangSchool of Sports Training, Wuhan Sports University, Wuhan 430079, China.
Chang LiuSchool of Sport Science, Beijing Sport University, Beijing 100084, China.ORCID 0000-0002-7867-6807

Funding

Fundamental Research Funds for the Central Public Welfare Research Institutes No.ZXKT22009National Natural Science Foundation of China No. 82304718Peking University Health Science Center for the Study on Effects of Anti-Aging Nutritional Interventions on Athletes' Skin Health No.YFF24000662、No.BSU20240500Peking University Medical-Qingyan Boshi Joint Laboratory for Skin Nutrition and Anti-Aging No.L202206Scientific and Technological Innovation Project of the China Academy of Chinese Medical Sciences No.CI2023E002
6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the effects of

methodsA randomized, double-blind, placebo-controlled trial was conducted with 48 male participants, including 24 resistance-trained and 24 untrained individuals. Participants were stratified by training status and randomly assigned to either the CD or placebo (PLAC) group. All subjects completed a standardized resistance training program three times per week for eight weeks. The CD group received 5 g of CD extract twice daily, while the PLAC group consumed a matched placebo. Assessments included one-repetition maximum (1RM) for bench press and squat, maximal voluntary isometric contraction (MVIC), and repetitions to failure (RTF). Blood biomarkers including serum testosterone, cortisol, C-reactive protein (CRP), and creatine kinase (CK) were also measured.

resultsNo significant differences in dietary energy intake or macro-nutrient composition were observed based on two 5-day dietary records collected before baseline testing and at the end of the intervention. Among untrained individuals, the CD group showed significantly greater improvements in 1RM bench press and squat compared with the PLAC group (

conclusionsDaily supplementation with 5 g of CD extract for eight consecutive weeks significantly enhanced muscle strength and endurance in males with different training backgrounds and facilitated post-exercise recovery by modulating hormonal responses and reducing stress levels and inflammation. These findings provide experimental evidence supporting the application of CD in sports nutrition.

Indexed as

CistancheDietary SupplementsMuscle StrengthPlant ExtractsAdultBiomarkersC-Reactive ProteinCreatine KinaseDouble-Blind MethodHumansHydrocortisoneIsometric ContractionMaleMuscle, SkeletalResistance TrainingTestosteroneBiomarkersC-Reactive ProteinCreatine KinaseHydrocortisonePlant ExtractsTestosteroneCistanche deserticola Y.C. Mamuscle recoverymuscle strengthresistance trainingtestosterone

Identifiers

PMID41010491
PMCPMC12472218

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.