Evidence map›Paper›PMID 41010521›Full record

ArticleNutrients2025

Xin Ma, Jiaxuan Chen, Rui Chen, Wenjiao Liang, Rui Huang, Lishiyuan Tang, Lichun Qian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xin MaKey Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Jiaxuan ChenHainan Institute of Zhejiang University, Sanya 572025, China.
Rui ChenHainan Institute of Zhejiang University, Sanya 572025, China.
Wenjiao LiangKey Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Rui HuangHainan Institute of Zhejiang University, Sanya 572025, China.
Lishiyuan TangKey Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Lichun QianKey Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-8699-1885

Funding

Zhejiang Province Science and Technology Commissioner Team Project (2025-2029). Zhejiang Province Science and Technology Commissioner Team Project (2025-2029)
6 · The paper itself

Abstract

backgroundLophatheri Herba, a traditional East Asian herb with documented food uses, contains bioactive flavonoids. This study investigated how

methodsFermented leaf extracts were analyzed via GC-MS/LC-MS for SCFAs and metabolites. Forty-eight mice were divided into control (standard diet) and three experimental groups (25, 50, 100 mg/kg/day fermented product). After a 4-week intervention, duodenal morphology, colonic cytokines (IL-6/IL-1β), and cecal microbiota were assessed.

resultsWe identified significant SCFAs optimization. Significantly increased: acetic acid; butyric acid (

conclusionsFermented Lophatheri Herba protects gut health through synergistic SCFAs optimization, flavonoid enrichment, and probiotic proliferation, supporting its potential as a microbiota-targeting functional food ingredient.

Indexed as

Aspergillus oryzaeFatty Acids, VolatileFermentationFlavonoidsGastrointestinal MicrobiomePlant ExtractsAnimalsCecumColonIntestinal MucosaMaleMicePlant LeavesFatty Acids, VolatileFlavonoidsPlant ExtractsAspergillus oryzae fermentationflavonoid metabolitesgut microbiotaLophatheri Herba leavesshort-chain fatty acids

Identifiers

PMID41010521
PMCPMC12472607

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.