ReviewJournal of clinical medicine2025
Current and Emerging Sedation Practices for Colonoscopy: A Narrative Review of Pharmacological Agents, High-Risk Populations, and Safety Considerations.
Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Total Colonic Decompression Fails to Decrease Post- Colonoscopy Abdominal Pain: A Double-Blind Randomized Controlled Trial.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026Trial
- A two-phase randomized study of oliceridine versus sufentanil for gastrointestinal endoscopy.Frontiers in pharmacology · 2026Trial
- Effectiveness of psychological intervention based on implicit theory combined with virtual reality in patients with unruptured intracranial aneurysm receiving their first cerebral angiography after flow-diverter stent implantation.Frontiers in psychiatry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colonoscopy is the gold standard for colorectal cancer screening and diagnosis of gastrointestinal disorders, yet the procedure can still provoke anxiety and pain in many patients. Advances in anesthesia and sedation techniques have significantly improved patient tolerance while maintaining procedural efficiency and safety. This review explores the physiological mechanisms of pain during colonoscopy, compares anesthetic and sedative agents-including newer drugs like remimazolam and dexmedetomidine-and evaluates emerging evidence from recent studies on sedation efficacy, safety, and patient outcomes. Special attention is given to high-risk patient populations, including those with obesity, obstructive sleep apnea, cardiovascular diseases, respiratory disorders and frailty syndrome. Propofol-based sedation remains the most commonly used agent for deep sedation. However, newer pharmacological agents with enhanced pharmacokinetic properties and improved safety profiles are increasingly influencing contemporary anesthesia practices. An individualized approach to sedation is essential. Incorporating current evidence into clinical decision-making optimizes both patient experience and procedural outcomes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.