Evidence map›Paper›PMID 41011452›Full record

ArticleMicroorganisms2025

Oral Microbiota Dysbiosis in Male HIV Patients: Comparative Analysis of Candidiasis and HPV-Associated Lesions.

Magnolia Del Carmen Ramírez-Hernández, Javier Gaytán-Cervantes, Carolina González-Torres, Miguel Ángel Loyola-Cruz, Rebeca Eunice García-Mendiola, Clemente Cruz-Cruz, Iliana Alejandra Cortés-Ortíz, Eduardo García-Moncada, Teresa López-Flores, Emilio Mariano Durán-Manuel and 14 more

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Magnolia Del Carmen Ramírez-HernándezHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0009-0005-9304-7047
Javier Gaytán-CervantesDivisión de Desarrollo de la Investigación, Centro Médico Nacional Siglo XXI, Mexico City 06720, Mexico.
Carolina González-TorresDivisión de Desarrollo de la Investigación, Centro Médico Nacional Siglo XXI, Mexico City 06720, Mexico.
Miguel Ángel Loyola-CruzHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0001-5383-8737
Rebeca Eunice García-MendiolaClínica Especializada Condesa Iztapalapa, Mexico City 09730, Mexico.
Clemente Cruz-CruzHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0003-1555-3102
Iliana Alejandra Cortés-OrtízHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0001-9409-5896
Eduardo García-MoncadaHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0001-9817-6183
Teresa López-FloresClínica Especializada Condesa Iztapalapa, Mexico City 09730, Mexico.
Emilio Mariano Durán-ManuelHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0001-8985-486X
Nancy Gómez-MancillaClínica Especializada Condesa Iztapalapa, Mexico City 09730, Mexico.
María Fernanda Oviedo-LópezClínica Especializada Condesa Iztapalapa, Mexico City 09730, Mexico.
Carlos Alberto Jiménez-ZamarripaSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-9195-746X
Araceli Rojas-BernabéSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-3851-5881
Omar Agni García-HernándezFacultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 54090, Mexico.ORCID 0000-0001-8807-1353
Jonathan Puente-RiveraHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0001-6941-6248
Adolfo López-OrnelasHospital Juárez de México, Mexico City 07760, Mexico.
Nayeli Goreti Nieto-VelázquezHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0001-5354-9900
Dulce Milagros Razo Blanco-HernándezHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0003-3869-344X
Julio César Castañeda-OrtegaFacultad de Biología, Universidad Veracruzana, Xalapa 91090, Mexico.ORCID 0000-0003-2663-9155
Benito Hernández-CastellanosFacultad de Biología, Universidad Veracruzana, Xalapa 91090, Mexico.
Gabriela Anaya-SaavedraPosgrado en Patología y Medicina Bucal, Universidad Autónoma Metropolitana, Mexico City 04960, Mexico.ORCID 0000-0002-8881-867X
Claudia Camelia Calzada-MendozaSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-5893-8566
Juan Manuel Bello-LópezHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0002-9957-3807

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive immune damage associated with Human Immunodeficiency Virus (HIV) alters mucosal homeostasis, favouring oral microbial imbalance and the development of opportunistic infections. The aim of this study was to characterize the composition and structure of the oral microbiota in different clinical conditions of HIV infection. A cross-sectional study was conducted in 99 Mexican men divided into five groups: HIV-negative controls, newly diagnosed without antiretroviral treatment, virally suppressed, with oral candidiasis, and with HPV infection. Metagenomic DNA was obtained from salivary samples, and the V1-V3 region of the 16S rRNA gene was massively sequenced. Taxonomic profiles, alpha/beta diversity, differential abundance, microbial co-occurrence networks and degree of dysbiosis were analysed. The results showed distinctive profiles between the groups. Alpha and beta diversity was significantly higher in the groups with oral

Indexed as

HIVmassive sequencingoral lesionsoral microbiota

Identifiers

PMID41011452
PMCPMC12473140

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.