ReviewMolecules (Basel, Switzerland)2025
Ferulic Acid: Mechanistic Insights and Multifaceted Applications in Metabolic Syndrome, Food Preservation, and Cosmetics.
Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- The Inclusion of Supercritical Fluid Extract ofAntioxidants (Basel, Switzerland) · 2026Article
- Unlocking the Potential ofFoods (Basel, Switzerland) · 2026Review
- From Glycation to Toxicity: α-Synuclein Oligomers, Oxidative Stress, and Multi-Targeted Protection by Trans-Ferulic Acid.Cell biochemistry and biophysics · 2026Article
- Article
- Quercetin: Mechanisms of Action, Clinical Evidence in Metabolic Syndrome, and Translational Opportunities in Food Preservation.Molecules (Basel, Switzerland) · 2026Review
- Ferulic Acid Modulates High Glucose-Induced MMP-1/TIMP-1 Imbalance and Enhances Wound Closure of Human Gingival Fibroblasts.Biomedicines · 2026Article
- Review
- Article
- Chemical Profiling, Pharmacological Activities, and Toxicity Assessment ofFood science & nutrition · 2026Article
- Fermented Rice Bran Enhances Rabbit Meat Quality and Nutritional Value via Metabolic Reprogramming and Enriched Nutrient Profiles.Animals : an open access journal from MDPI · 2026Article
- Molecular Association Between Short Linear Maltodextrin and Ferulic Acid and the Exploration of Its Applicability.Polymers · 2026Article
- Optimization of Aspergillus Niger fermentation for enzyme production and enzymatic hydrolysis of wheat bran for total ferulic acid via RSM.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ferulic acid (FA) is a plant-derived phenolic compound recognized for its potent antioxidant and anti-inflammatory properties, with growing applications in health, food, and cosmetic sciences. This review presents a comprehensive overview of recent in vivo and clinical evidence, emphasizing its effects on metabolic syndrome (MetS) and its technological applications in food and cosmetics. FA has shown preventive and therapeutic potential in managing MetS by improving glucose and lipid metabolism, lowering blood pressure, reducing oxidative stress, and modulating inflammatory and microbiota-related pathways. In food systems, FA serves as a multifunctional additive, exhibiting antimicrobial activity, inhibition of lipid oxidation, stabilization of pigments, and protection of sensitive nutrients that extend shelf life and enhance nutritional quality. Its inclusion in cosmetic formulations further demonstrates synergistic photoprotective effects with conventional UV filters, antioxidant support for vitamins C and E, and anti-aging and skin-brightening properties, although formulation challenges remain. Collectively, FA's pleiotropic actions and compatibility with clean-label trends highlight its value as a natural bioactive. Continued research on improving its stability, bioavailability, and clinical validation will support its broader integration into functional food, nutraceutical, and cosmeceutical products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.