In Vivo Anti-Inflammatory Evaluation and In Silico Physicochemical Characterization of Flavanones from

Berenice Andrade-Carrera, Valeri Domínguez-Villegas, Ana Cristina Calpena, María Luisa Garduño-Ramírez

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Berenice Andrade-CarreraFacultad de Nutrición, Universidad Autónoma del Estado de Morelos, Cuernavaca 62350, Morelos, Mexico.ORCID 0000-0002-0625-5579

Valeri Domínguez-VillegasFacultad de Ciencias Químicas e Ingeniería, Universidad Autónoma del Estado de Morelos, Cuernavaca 62210, Morelos, Mexico.ORCID 0000-0001-9366-8744

Ana Cristina CalpenaDepartment of Pharmacy, Pharmaceutical Technology and Physical Chemistry, School of Pharmacy and Food Sciences, University of Barcelona, 27-31 Joan XXIII Av., 08028 Barcelona, Spain.ORCID 0000-0002-4989-4821

María Luisa Garduño-RamírezCentro de Investigaciones Químicas, Instituto de Investigación en Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos, Cuernavaca 62210, Morelos, Mexico.ORCID 0000-0001-5041-5587

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inflammatory response is a defence mechanism triggered by tissue damage, aiming to eliminate harmful agents and initiate healing. Conventional anti-inflammatory drugs, such as NSAIDs and corticosteroids, are widely used but often cause severe side effects. Flavonoids, particularly flavanones, have shown significant anti-inflammatory activity with fewer adverse effects. In this study, eight analogues (

Indexed as

Anti-Inflammatory AgentsFlavanonesPlant LeavesAnimalsComputer SimulationDisease Models, AnimalEdemaMaleMiceMolecular StructurePlant ExtractsAnti-Inflammatory AgentsFlavanonesPlant Extractsanti-inflammatory activityEysenhardtia platycarpaflavanonesSAR

Identifiers

PMID41011621

DOI10.3390/molecules30183728

PMCPMC12472972

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.