Evidence map›Paper›PMID 41011628›Full record

ArticleMolecules (Basel, Switzerland)2025

Substituent Effect in Histamine and Its Impact on Interactions with the G Protein-Coupled Human Receptor H

Anna Jezuita, Małgorzata Makowska-Janusik, Krzysztof Ejsmont, Wojciech Marczak

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna JezuitaFaculty of Science and Technology, Jan Dlugosz University, Al. Armii Krajowej 13/15, 42-200 Czestochowa, Poland.
Małgorzata Makowska-JanusikFaculty of Science and Technology, Jan Dlugosz University, Al. Armii Krajowej 13/15, 42-200 Czestochowa, Poland.ORCID 0000-0002-0946-0025
Krzysztof EjsmontDepartment of Chemistry and Pharmacy, University of Opole, Oleska 48, 45-052 Opole, Poland.ORCID 0000-0003-1426-3322
Wojciech MarczakFaculty of Science and Technology, Jan Dlugosz University, Al. Armii Krajowej 13/15, 42-200 Czestochowa, Poland.ORCID 0000-0002-7323-8293

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutral and protonated histamine tautomers, mono-substituted with twelve functional groups, were studied theoretically as isolated molecules and complexes with the H

Indexed as

HistamineReceptors, Histamine H1HumansHydrogen BondingModels, MolecularMolecular StructureProtein BindingQuantum TheoryHistamineReceptors, Histamine H1aromaticitycSARDFTelectronic structurehistamineHOMAhuman receptor H1hydrogen bondsimidazoleimidazolium

Identifiers

PMID41011628
PMCPMC12472401

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.