Multidisciplinary Bioanalytical Approach to Assess the Anti-Aging Properties of Flower Petals-A Promising Sustainable Cosmetic Ingredient.

Đurđa Ivković, Milan Senćanski, Mirjana Novković, Jelena Stojković-Filipović, Jelena Trifković, Petar Ristivojević, Maja Krstić Ristivojević

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Article in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Đurđa IvkovićInnovative Centre of the Faculty of Chemistry Ltd., Studentski Trg 12-16, 11158 Belgrade, Serbia.ORCID 0000-0003-0571-9623

Milan SenćanskiLaboratory of Bioinformatics and Computational Chemistry, Institute of Nuclear Sciences Vinca, National Institute of the Republic of Serbia, University of Belgrade, 11001 Belgrade, Serbia.ORCID 0000-0002-7296-3223

Mirjana NovkovićGroup for Muscle Cellular and Molecular Biology IMGGE, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042 Belgrade, Serbia.ORCID 0000-0003-0788-9765

Jelena Stojković-FilipovićClinic of Dermatovenereology, University Clinical Center of Serbia, University of Belgrade-Faculty of Medicine, Dr Subotića Starijeg 8, 11000 Belgrade, Serbia.

Jelena TrifkovićDepartment of Analytical Chemistry, University of Belgrade-Faculty of Chemistry, Studentski trg 12-16, 11158 Belgrade, Serbia.

Petar RistivojevićDepartment of Analytical Chemistry, University of Belgrade-Faculty of Chemistry, Studentski trg 12-16, 11158 Belgrade, Serbia.ORCID 0000-0001-6106-1454

Maja Krstić RistivojevićDepartment of Biochemistry, University of Belgrade-Faculty of Chemistry, Studentski trg 12-16, 11158 Belgrade, Serbia.ORCID 0000-0002-8794-9408

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing demand for natural, safe, and sustainable ingredients is driving innovation in cosmetic science. This study assessed the anti-aging potential of 17 petal extracts using a multidisciplinary bioanalytical approach. In vitro spectrophotometric assays evaluated anti-wrinkle (anti-elastase), anti-pigmentation (anti-tyrosinase), and antioxidant (DPPH, ABTS) activities, while cytotoxicity was tested on HaCaT keratinocytes. Chemical profiling using HPTLC and UHPLC-MS/MS identified 17 phenolic compounds. For the first time, petals from prairie rose (

Indexed as

anti-agingcultivated petalshigh performance thin layer chromatography (HPTLC)liquid chromatography coupled mass spectrometry (LC-MS)molecular dockingphenolic profilingsustainable cosmetics

Identifiers

PMID41012020

DOI10.3390/plants14182869

PMCPMC12473510

What Socratic holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.