Evidence mapPaperPMID 41012449Full record

ArticlePharmaceutics2025

Exploring Experimental and Statistical Approaches to Control Oversensitivity of In Vitro Permeability to Excipient Effects.

Mauricio A García, Alexis Aceituno, Nicole B Díaz, Eduardo M Tapia, Danae Contreras, Constanza López-Lagos, Virginia Sánchez, Pablo M González

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mauricio A GarcíaDepartamento de Farmacia, Escuela de Química y Farmacia, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.ORCID 0000-0001-5618-3318
Alexis AceitunoNational Drug Agency Department, Instituto de Salud Pública de Chile (ISP), Santiago 7780050, Chile.ORCID 0000-0002-0960-8413
Nicole B DíazDepartamento de Farmacia, Escuela de Química y Farmacia, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.ORCID 0009-0008-6770-2361
Eduardo M TapiaDepartamento de Farmacia, Escuela de Química y Farmacia, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.
Danae ContrerasDepartamento de Farmacia, Escuela de Química y Farmacia, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.
Constanza López-LagosDepartamento de Farmacia, Escuela de Química y Farmacia, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.
Virginia SánchezEscuela de Química y Farmacia, Universidad de Valparaíso, Valparaíso 2340000, Chile.ORCID 0009-0006-7675-4396
Pablo M GonzálezInnovation and Biopharmaceutical Evaluation Center (IBECenter), Av. México 715, Recoleta, Santiago 8441536, Chile.

Funding

Agencia Nacional de Investigación y Desarrollo 16I10142
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

common excipientscomparative permeabilityexcipient effectMDCK-wt monolayersoral absorptionpermeabilitystatistical comparison permeability

Identifiers

PMID41012449
PMCPMC12472618

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.