Evidence map›Paper›PMID 41012941›Full record

ArticleSensors (Basel, Switzerland)2025

High-Sensitivity MXene-Functionalized Photonic Crystal Fiber Surface Plasmon Resonance Sensor with Dual Rectangular Grooves for Cancer Detection.

Min Lu, Yan He, Shuyu Xi, Pufan Zhong, Yu Zhang, He Tian, Yongmei Wang, Hanglin Lu, Junhui Hu, Jian Tang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Min LuUniversity Engineering Research Center of Advanced Functional Materials and Intelligent Sensing, College of Physics and Technology, Guangxi Normal University, Guilin 541004, China.
Yan HeUniversity Engineering Research Center of Advanced Functional Materials and Intelligent Sensing, College of Physics and Technology, Guangxi Normal University, Guilin 541004, China.
Shuyu XiUniversity Engineering Research Center of Advanced Functional Materials and Intelligent Sensing, College of Physics and Technology, Guangxi Normal University, Guilin 541004, China.
Pufan ZhongUniversity Engineering Research Center of Advanced Functional Materials and Intelligent Sensing, College of Physics and Technology, Guangxi Normal University, Guilin 541004, China.
Yu ZhangUniversity Engineering Research Center of Advanced Functional Materials and Intelligent Sensing, College of Physics and Technology, Guangxi Normal University, Guilin 541004, China.
He TianUniversity Engineering Research Center of Advanced Functional Materials and Intelligent Sensing, College of Physics and Technology, Guangxi Normal University, Guilin 541004, China.
Yongmei WangUniversity Engineering Research Center of Advanced Functional Materials and Intelligent Sensing, College of Physics and Technology, Guangxi Normal University, Guilin 541004, China.
Hanglin LuUniversity Engineering Research Center of Advanced Functional Materials and Intelligent Sensing, College of Physics and Technology, Guangxi Normal University, Guilin 541004, China.ORCID 0009-0004-9366-4849
Junhui HuUniversity Engineering Research Center of Advanced Functional Materials and Intelligent Sensing, College of Physics and Technology, Guangxi Normal University, Guilin 541004, China.ORCID 0000-0003-0472-6178
Jian TangUniversity Engineering Research Center of Advanced Functional Materials and Intelligent Sensing, College of Physics and Technology, Guangxi Normal University, Guilin 541004, China.

Funding

Guangxi Zhuang Autonomous Region, National Natural Science Foundation of China 2022GXNSFDA080006, 62265002
6 · The paper itself

Abstract

Early detection of cancer remains a key challenge because current SPR-PCF sensors lack both sensitivity and robust light-analyte interaction. To overcome these limitations, this study proposed and validated an SPR biosensor utilizing MXene-functionalized PCF. By introducing a composite structure of MXene nanomaterials and Au, the detection performance of the sensor was significantly improved. The sensor adopts a circular air hole arrangement and double-groove morphology design and leverages MXene's high conductivity and gold's chemical stability to simultaneously enhance plasmonic coupling and biocompatibility. Through FEM-based structural optimization of the air hole diameter, Au layer thickness, and groove shape, the sensor exhibited outstanding refractive-index detection performance with a wavelength sensitivity of 11,072 nm/RIU, an impressive quality factor reaching 201.3 RIU

Indexed as

Biosensing TechniquesNeoplasmsSurface Plasmon ResonanceCell Line, TumorEarly Detection of CancerGoldHeLa CellsHumansNanostructuresNitritesTransition ElementsGoldMXeneNitritesTransition Elementsbiosensorsfinite element method (FEM)MXenephotonic crystal fiber (PCF)surface plasmon resonance (SPR)

Identifiers

PMID41012941
PMCPMC12473927

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.