Evidence map›Paper›PMID 41013199›Full record

ArticleBMC genomics2025

Genome-wide analysis of the BES1 gene family reveals their involvement in grain development of Triticum aestivum L.

Yang Zhang, Yanmin Xu, Yulu Mao, Min Wang, Xiaoli Li, Lanfang Jiang, Jianyu Hao, Dingyi Zhang, Hutai Ji, Xiaofei Ma

Abstract read
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yang Zhang *Wheat Research Institute, Shanxi Agricultural University, Linfen, 041000, China.
Yanmin Xu *Wheat Research Institute, Shanxi Agricultural University, Linfen, 041000, China.
Yulu MaoWheat Research Institute, Shanxi Agricultural University, Linfen, 041000, China.
Min WangWheat Research Institute, Shanxi Agricultural University, Linfen, 041000, China.
Xiaoli LiWheat Research Institute, Shanxi Agricultural University, Linfen, 041000, China.
Lanfang JiangWheat Research Institute, Shanxi Agricultural University, Linfen, 041000, China.
Jianyu HaoWheat Research Institute, Shanxi Agricultural University, Linfen, 041000, China.
Dingyi ZhangWheat Research Institute, Shanxi Agricultural University, Linfen, 041000, China.
Hutai JiWheat Research Institute, Shanxi Agricultural University, Linfen, 041000, China. sxjihut@163.com.
Xiaofei MaWheat Research Institute, Shanxi Agricultural University, Linfen, 041000, China. nongxue06123@163.com.

Funding

China Agriculture Research System Wheat, CARS-03-54Fundamental Research Program of Shanxi Province 202303021222075Project of Science and Technology Innovation Fund of Shanxi Agricultural University 2023BQ40the earmarked fund for Modern Agro-industry Technology Research System 2024CYJSTX02-22
6 · The paper itself

Abstract

backgroundThe BRI1-EMS SUPPRESSOR1 (BES1) gene family was initially recognized as specifically regulating brassinosteroids to mediate gene expression, which is of vital significance for plant growth and enhancing stress tolerance. Despite extensive studies in multiple plants, there has been a lack of focused and systematic analysis of BES1s in wheat grains.

resultsIn this study, we performed a comprehensive bioinformatics analysis of the BES1s in wheat, utilizing the latest genomics data from the Chinese Spring. A total of 19 TaBES1 were identified. An analysis of conserved domains, phylogenetic relationships, and gene structure revealed a significant level of conservation among TaBES1s. A gene collinearity analysis indicated that fragment duplication was the primary mechanism responsible for the amplification of TaBES1s. Furthermore, cis-acting elements within the promoters of TaBES1s were found to be implicated in grain development. Subsequently, SNP analysis revealed the genetic variation of TaBES1s across different wheat varieties. Moreover, published RNA-seq data were used, and RNA-seqs of Yaomai36, Pinyu8175, Pinyu8155, and Yaomai30 were performed to identify TaBES1s influencing grain development. Finally, the research found that TaBES1s had no self-activating activity in wheat. However, the interacting proteins of TaBES1-1 and TaBES1-4 are not only involved in starch metabolism but may also be implicated in cell signal transduction.

conclusionsThis study further confirmed the potential function of BES1s in the grain development of wheat. These findings that BES1s play a regulatory role in wheat grain development provide a foundation for further understanding the molecular mechanisms underlying crop grain development.

Indexed as

Edible GrainMultigene FamilyPlant ProteinsTriticumGene Expression Regulation, PlantGenome, PlantPhylogenyPolymorphism, Single NucleotidePlant ProteinsBES1 gene familyBioinformatics analysisExpression analysisGrain developmentWheat

Identifiers

PMID41013199
PMCPMC12465741

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.