Evidence map›Paper›PMID 41014054›Full record

ArticleJournal of cellular physiology2025

PBMCs Mitochondrial Respiration and Its Relation to Immunity, Fitness, and Metabolic Risk in the Healthy Elderly.

Kristina Gebhardt, Anne Hebecker, Natascha Sommer, Robert Ringseis, Klaus Eder, Magdalena Huber, Hartmann Raifer, Karsten Krüger, Christopher Weyh

Abstract read
In one paragraph

Article in Journal of cellular physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kristina GebhardtDepartment of Exercise Physiology and Sports Therapy, Institute of Sports Science, Justus-Liebig-University, Giessen, Germany.
Anne HebeckerDepartment of Exercise Physiology and Sports Therapy, Institute of Sports Science, Justus-Liebig-University, Giessen, Germany.
Natascha SommerDepartment of Internal Medicine, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Excellence Cluster Cardio-Pulmonary Institute (CPI), Justus-Liebig University, Giessen, Germany.
Robert RingseisInstitute of Animal Nutrition and Nutrition Physiology, Justus Liebig University Giessen, Giessen, Germany.
Klaus EderInstitute of Animal Nutrition and Nutrition Physiology, Justus Liebig University Giessen, Giessen, Germany.
Magdalena HuberInstitute for Systems Immunology, Center for Tumor and Immunology, Marburg, Germany.
Hartmann RaiferInstitute for Systems Immunology, Center for Tumor and Immunology, Marburg, Germany.
Karsten KrügerDepartment of Exercise Physiology and Sports Therapy, Institute of Sports Science, Justus-Liebig-University, Giessen, Germany.ORCID 0000-0003-1506-8254
Christopher WeyhDepartment of Exercise Physiology and Sports Therapy, Institute of Sports Science, Justus-Liebig-University, Giessen, Germany.

Funding

This study was funded by the Forschungscampus Mittelhessen, Flexi Fund Project number 20121_1_1_10.
6 · The paper itself

Abstract

Mitochondrial function plays a central role in regulating immunological and metabolic processes, particularly during successful aging. This cross-sectional study aimed to investigate associations between mitochondrial respiration of peripheral blood mononuclear cells (PBMCs; MR

Indexed as

AgingLeukocytes, MononuclearMitochondriaAgedCD4-Positive T-LymphocytesCell RespirationCross-Sectional StudiesCytokinesFemaleHumansInflammationMaleMiddle AgedOxygen ConsumptionRisk FactorsCytokinesagingcell respirationimmune systeminflammationmitochondriaperipheral blood mononuclear cellsphysical fitness

Identifiers

PMID41014054
PMCPMC12475958

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.