Evidence map›Paper›PMID 41015027›Full record

ArticleCell reports methods2025

Metabolic profiling of antigen-specific CD8

Nils Mülling, J Fréderique de Graaf, Graham A Heieis, Kristina Boss, Benjamin Wilde, Bart Everts, Ramon Arens

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Cell cycle arrest enhances CD8Nature immunology · 2026
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nils MüllingDepartment of Immunology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands; Department of Nephrology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
J Fréderique de GraafDepartment of Immunology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands.
Graham A HeieisLeiden University Center of Infectious Diseases, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands.
Kristina BossDepartment of Nephrology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
Benjamin WildeDepartment of Nephrology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
Bart EvertsLeiden University Center of Infectious Diseases, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands.
Ramon ArensDepartment of Immunology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands. Electronic address: r.arens@lumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytotoxic CD8

Indexed as

AntigensCD8-Positive T-LymphocytesMetabolomeAnimalsCells, CulturedCOVID-19CytomegalovirusCytomegalovirus InfectionsFemaleFlow CytometryHumansLymphocyte ActivationMaleMetabolomicsMiceMice, Inbred C57BLAntigensantigen-specificCP: immunologyCP: metabolismmetabolismspectral flow cytometryT cell

Identifiers

PMID41015027
PMCPMC12570331

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.