ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2025
Effect of -deficiency constitution on cognitive impairment in cerebral small vessel disease and its neuroimaging mechanism.
Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Antihypertensive effect of acupuncture involve reshaping gut microbiota and alleviating gut inflammation in spontaneously hypertensive rats.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026Article
- Advances in brain MRI for CAD-associated cognitive impairment with supplementary perspectives from traditional Chinese medicine.Frontiers in medicine · 2026Review
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3 authors.
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Abstract
objectiveTo explore the effect of Traditional Chinese Medicine (TCM) constitution on cognitive impairment (CI) in patients with cerebral small vessel disease (CSVD) and its underlying neuroimaging mechanism and to provide countermeasures for health management of CSVD patients.
methodsA total of 241 CSVD patients were recruited from the Department of Neurology. All subjects underwent head magnetic resonance imaging (MRI), Chinese Medicine Questionnaire (CCMQ) and cognitive function examination. The CSVD patients were divided according to the Montreal Cognitive Assessment (MoCA) score into a normal cognitive group (73 cases) and a CI group (168 cases). Logistic regression was used to analyse the risk constitution of CSVD-CI and to construct a risk prediction model. 3DT1 MRI images and FreeSurfer 6.0 software (Athinoula A. Martinos, Boston, MA, USA) were used to further explore the involvement of hippocampal subregion volume in patients with at-risk constitution and its correlation with cognitive function.
resultsLogistic regression analysis showed that
conclusionCSVD patients with YADC are more prone towards developing CI, and asymmetric atrophy of the hippocampus might be the underlying neuroimaging mechanism. In particular, the volume of the left whole hippocampus and the left hippocampal molecular layer correlated significantly with general cognitive function.
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