Evidence map›Paper›PMID 41015923›Full record

ArticleWomen's health (London, England)

Salivary BDNF to predict at-risk status of eating disorders in young nutritionist Jordanian females: Results from a preliminary multistage study.

Aseel AlSaleh, Hebah Abdalla Ali, Amani Ali Almasri, Razan Mahmoud Omoush, Adam Tawfiq Amawi, Mohammed Ahmed Alkharisi, Seithikurippu R Pandi-Perumal, Khaled Trabelsi, Hadeel Ghazzawi, Haitham Jahrami

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Article in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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10 authors.

Aseel AlSalehAseel AlSaleh Department of Family and Community Medicine, College of Medicine and Health Sciences, Arabian Gulf University, Manama, Bahrain.ORCID 0000-0003-4652-2341
Hebah Abdalla AliDepartment of Nutrition and Food Technology, School of Agriculture, The University of Jordan, Amman, Jordan.
Amani Ali AlmasriDepartment of Nutrition and Food Technology, School of Agriculture, The University of Jordan, Amman, Jordan.ORCID 0009-0004-6534-7790
Razan Mahmoud OmoushDepartment of Nutrition and Food Technology, School of Agriculture, The University of Jordan, Amman, Jordan.
Adam Tawfiq AmawiSchool of Sport Sciences, Department of Movement Sciences and Sports Training, The University of Jordan, Amman, Jordan.
Mohammed Ahmed AlkharisiCollege of Medicine and Medical Science, Arabian Gulf University, Manama, Bahrain.
Seithikurippu R Pandi-PerumalCentre for Research and Development, Chandigarh University, Mohali, Punjab, India.
Khaled TrabelsiSchool of Sport Sciences, Department of Movement Sciences and Sports Training, The University of Jordan, Amman, Jordan.
Hadeel GhazzawiDepartment of Nutrition and Food Technology, School of Agriculture, The University of Jordan, Amman, Jordan.ORCID 0000-0003-3045-4153
Haitham JahramiGovernment Hospitals, Manama, Bahrain.ORCID 0000-0001-8990-1320

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrain-derived neurotrophic factor (BDNF) is associated with the development of different psychiatric conditions, including eating disorders (EDs).

objectivesTo investigate the salivary BDNF's ability to act as a potential biomarker for detecting the risk of developing EDs among young females. DESIGN AND

methodsA cross-sectional study was carried out in Amman, Jordan, with a total of 216 nutrition students completing the Eating Attitudes Test-26 (EAT-26) to assess the risk of developing EDs, the Cohens' Perceived Stress Scale-10 (PSS-10) to measure stress levels, and the International Physical Activity Questionnaire-Short Form (IPAQ-SF) to assess physical activity levels. Dietary intake was analyzed using a semiquantitative food frequency questionnaire. A nested sample of 34 females from both extreme EDs was selected and tested for salivary BDNF levels.

resultsThe nested sample of 34 female nutrition students 22.00 (2.75) years old with body mass index (BMI) of 23.60 (3.35) kg/m

conclusionBDNF is not a robust biomarker of risk for EDs. The changes in salivary BDNF levels could reflect individual ED eating patterns rather than indicating a direct causative role in the disorder's development. According to our results, psychiatric consultation for ED detection remains the gold standard for diagnosis and treatment.

Indexed as

Brain-Derived Neurotrophic FactorFeeding and Eating DisordersSalivaAdultBiomarkersBody Mass IndexCross-Sectional StudiesFemaleHumansJordanRisk FactorsStudentsSurveys and QuestionnairesYoung AdultBDNF protein, humanBiomarkersBrain-Derived Neurotrophic Factorbrain-derived neurotrophic factordietary intakedisordered eating riskmetabolic equivalentperceived stress levelsyoung nutritionist Jordanian female adults

Identifiers

PMID41015923
PMCPMC12477397

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.