Evidence map›Paper›PMID 41017675›Full record

ArticleNeural regeneration research2026

Artificial intelligence and peripheral neuropathies: Strategies for the development, application, and repair of regenerative biomaterials.

Zixu Zhang, Yi Yao, Zitao Wang, Huiyuan Bai, Maorong Jiang, Min Cai, Dengbing Yao

Abstract read
In one paragraph

Article in Neural regeneration research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zixu ZhangSchool of Life Sciences, Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu Province, China.
Yi YaoSchool of Public Health, Nantong University, Nantong, Jiangsu Province, China.
Zitao WangMedical School of Nantong University, Nantong, Jiangsu Province, China.
Huiyuan BaiSchool of Life Sciences, Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu Province, China.
Maorong JiangSchool of Life Sciences, Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu Province, China.
Min CaiMedical School of Nantong University, Nantong, Jiangsu Province, China.
Dengbing YaoSchool of Life Sciences, Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu Province, China.ORCID 0000-0002-5177-0318

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional repair methods for peripheral neuropathies, such as autologous and allogeneic nerve grafts, face limitations, while peripheral nerve regeneration materials have emerged as a promising alternative. However, current biomaterials are mostly single-functional and insufficient in modulating the regenerative microenvironment. This review explores the application of artificial intelligence in the development of neural regenerative biomaterials, focusing on material design, performance prediction, and virtual experiments. Artificial intelligence has the potential to optimize material properties through machine learning and deep learning, predict material performance, and enhance nerve regeneration. Recent studies have demonstrated the ability of artificial intelligence to design biomaterials with improved biocompatibility and mechanical properties, as well as to accurately predict outcomes of nerve regeneration. However, several challenges remain, such as data integration, algorithm complexity, and ensuring clinical translation. The promising future of intelligent research and development in biomaterials lies in personalized treatment strategies, coupled with the integration of advanced technologies such as artificial intelligence and 3D bioprinting, to create more efficient neural repair materials. This review highlights the transformative potential of artificial intelligence in advancing peripheral nerve repair and improving patient outcomes.

Indexed as

3D printingartificial intelligencebiomaterialsbioresorbable scaffoldsdeep learningmachine learningnerve conduitsnerve regenerationperipheral nerve injuriestissue engineering

Identifiers

PMID41017675
PMCPMC13557695

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.