ArticleIbrain2025
Histological investigation of the interthalamic adhesion and periventricular region: Evidence for midline neural connectivity.
Article in Ibrain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The interthalamic adhesion (IA), which may not be present in all humans, is a midline structure that connects the two thalami within the brain's third ventricle. A review of the known literature regarding the IA shows few histological studies and controversy regarding the organization of neurons within this region. This study conducted an anatomical investigation of the human IA in adult South African samples. Samples were obtained from 20 human adult embalmed cadavers: 11 from brains with a visible IA and 9 from brains without this feature. All the samples were harvested using sagittal sections of the area. Three additional samples were sectioned horizontally, yielding 33 tissue blocks. Before observation, these samples were appropriately processed for light microscopy and stained with haematoxylin and eosin, as well as cresyl violet. The results showed that no specific structural arrangements of the neurons were identifiable. The appearance appeared random, except for a distinguishable range in the frequency and dispersion of specific cells upon basic observation. Microglia were the most abundant cell type, and blood vessels were also observed. This study reports a novel inspection of the general histology of the thalamus, specifically of the IA and the periventricular (PVR) region, in midsagittal sections and three horizontal sections. This study confirmed the presence of pyramidal neurons within the IA, forming a bridge between the PVR region of the thalami, thus providing evidence to suggest that the IA could serve as a potential bridge for neural connections crossing over the brain's midline.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.