Evidence map›Paper›PMID 41018261›Full record

ArticleFrontiers in cell and developmental biology2025

Changzhi Huang, Xiaofeng Liu, Liang Lin, Shimin Zhang, Nanyi Xu, Xiaoyong Wang, Jiuzao Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Changzhi Huang *Department of Joint Surgery and Sports Medicine, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China.
Xiaofeng Liu *Department of Orthopaedics, Shanghai Sixth People's Hospital Fujian, Quanzhou, Fujian, China.
Liang Lin *Department of Orthopaedics, The First Hospital of Putian City, Putian, Fujian, China.
Shimin ZhangNingde Clinical Medical College of Fujian Medical University, Ningde, Fujian, China.
Nanyi XuNingde Clinical Medical College of Fujian Medical University, Ningde, Fujian, China.
Xiaoyong WangDepartment of Joint Surgery and Sports Medicine, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China.
Jiuzao LinDepartment of Joint Surgery and Sports Medicine, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgroud: Bone defect repair is clinically challenging due to the limitations of traditional treatments. Tissue engineering holds great potential for constructing bone substitutes. This study evaluates the osteogenic capability of calcitonin gene-related peptide (CGRP)-induced rat adipose-derived stem cells (ADSCs) combined with calcium alginate (CaAlg) scaffolds both Methods: ADSCs were isolated from rat inguinal fat pads, cultured, and characterized at passage 3. For Results: ADSCs had clear surface antigen characteristics and displayed an "S"-shaped proliferation curve post-osteogenic induction. Conclusion: These findings indicate that CGRP can induce ADSCs combined with CaAlg scaffolds to form tissue-engineered bone

Indexed as

adipose-derived stem cellscalcitonin gene-related peptidecalcium alginate hydrogelosteogenic differentiationthree-dimensional culturetissue engineering

Identifiers

PMID41018261
PMCPMC12463825

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.