Evidence map›Paper›PMID 41018339›Full record

ReviewCureus2025

Postoperative Intra-abdominal Abscess Following General Surgery: A Systematic Review of Risk Factors, Prevention, and the Role of Laparotomy.

Mawada Taha, Mohamed K Abouelsadat, Mohamed Elfakharany, Abdelrahman Ibrahim, Ahmed M Abufouda, Nasratullah Barai, Jarallah H J Alkhazendar, Aliaa H Alkhazendar, Anwar Al-Kassar, Ahmed Khan

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mawada TahaGeneral Surgery, The National Ribat University, Khartoum , SDN.
Mohamed K AbouelsadatVascular Surgery, Royal Free Hospital, London, GBR.
Mohamed ElfakharanyGeneral Surgery, Health Education England, Yorkshire and The Humber Deanery, Leeds, GBR.
Abdelrahman IbrahimTrauma and Orthopedic, University Hospitals of North Midlands NHS Trust, Stoke-on-Tent, GBR.
Ahmed M AbufoudaColorectal Surgery, Mansoura Teaching Hospitals, Mansoura, EGY.
Nasratullah BaraiGeneral Surgery, Royal Medical Complex, Kabul, AFG.
Jarallah H J AlkhazendarGeneral and Emergency Surgery, East and North Hertfordshire NHS Trust, Lister Hospital, Stevenage, GBR.
Aliaa H AlkhazendarSurgery, The Islamic University of Gaza, Gaza, PSE.
Anwar Al-KassarVascular Surgery, Countess of Chester Hospital, Chester, GBR.
Ahmed KhanMedicine, Elizabethtown College, Islamabad, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative intra-abdominal abscess (PIAA) is a significant complication following general abdominal surgery, contributing to increased morbidity and mortality. This systematic review was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines, with a comprehensive search of multiple databases including PubMed, Embase, Scopus, and the Cochrane Library up to July 2025. Studies were selected based on predefined PICO (Population, Intervention, Comparison, Outcome) criteria, focusing on adult patients undergoing abdominal surgery and assessing risk factors, prevention, and management strategies for PIAA. Five eligible studies involving 3,537 patients were included and analyzed. Key risk factors identified included perforated appendicitis, intraoperative contamination, elevated National Nosocomial Infections Surveillance (NNIS) scores, preoperative radiation, and splenectomy. Preventive measures such as targeted perioperative antibiotic prophylaxis and selective surgical drainage have demonstrated efficacy in reducing abscess incidence. Percutaneous drainage is generally preferred as the initial intervention due to its minimally invasive nature and favorable outcomes, while laparotomy remains necessary for complex abscesses involving multiloculated collections or anastomotic leaks. The routine use of prophylactic drains remains controversial and may increase postoperative complications. Effective management of PIAA requires careful risk assessment, individualized preventive strategies, and prompt source control. Further well-designed randomized controlled trials are needed to establish standardized treatment protocols and optimize patient outcomes.

Indexed as

general surgeryintra-abdominal infectionlaparotomypostoperative abscesspreventionrisk factorssource control

Identifiers

PMID41018339
PMCPMC12466042

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.